2-Amino-6-chloropyrazine

Base Information Edit

Chemical Name:2-Amino-6-chloropyrazine
CAS No.:33332-28-4
Molecular Formula:C4H4ClN3
Molecular Weight:129.549
Hs Code.:29339900
European Community (EC) Number:636-487-7
UNII:CVL0CMW8XR
DSSTox Substance ID:DTXSID0067761
Nikkaji Number:J88.860E
Wikidata:Q27093316
Metabolomics Workbench ID:146890
ChEMBL ID:CHEMBL191632
Mol file:33332-28-4.mol

Synonyms:2-AMINO-6-CHLOROPYRAZINE;33332-28-4;6-chloropyrazin-2-amine;2-chloro-6-aminopyrazine;Pyrazinamine, 6-chloro-;2-Pyrazinamine, 6-chloro-;6-CHLORO-2-PYRAZINAMINE;CVL0CMW8XR;MFCD00055024;2-amino-6-chloro-pyrazine;6-Chloro-pyrazin-2-ylamine;CHEMBL191632;AI3-61778;6-chloropyrazin-2-ylamine;1wcc;CIG;UNII-CVL0CMW8XR;D0W0PF;2-amino-6-chloro pyrazine;SCHEMBL67803;6-chloro-pyrazin-2-yl-amine;6-chloropyrazin-2-amine, 5;Pyrazine, 2-amino-6-chloro-;DTXSID0067761;BDBM24626;6-AMINO-2-CHLOROPYRAZINE;6-CHLORO-2-AMINOPYRAZINE;BCP23199;CS-D1094;BBL028064;STL146905;2-amino-6-chloropyrazine, AldrichCPR;AKOS005257543;AC-1747;DB02297;PB12992;PS-3478;SY007507;A5946;AM20070343;FT-0602131;EN300-60304;6-Chloropyrazin-2-amine;Q-103329;Q27093316;Z850999210

Suppliers and Price of 2-Amino-6-chloropyrazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-2-pyrazinamine
100g
$ 445.00

TRC
6-Chloro-2-pyrazinamine
50g
$ 195.00

TCI Chemical
2-Amino-6-chloropyrazine >98.0%(GC)
1g
$ 26.00

TCI Chemical
2-Amino-6-chloropyrazine >98.0%(GC)
5g
$ 118.00

SynQuest Laboratories
2-Amino-6-chloropyrazine 98%
100 g
$ 220.00

SynQuest Laboratories
2-Amino-6-chloropyrazine 98%
25 g
$ 56.00

SynQuest Laboratories
2-Amino-6-chloropyrazine 98%
5 g
$ 16.00

SynChem
6-Chloropyrazin-2-ylamine 95%
5 g
$ 20.00

Oakwood
2-Amino-6-chloropyrazine 98%
5g
$ 10.00

Oakwood
2-Amino-6-chloropyrazine 98%
1g
$ 9.00

Total 120 raw suppliers

Chemical Property of 2-Amino-6-chloropyrazine Edit

Chemical Property:

Appearance/Colour:Colorless or off-white solid
Vapor Pressure:0.00329mmHg at 25°C
Melting Point:150-152 °C
Refractive Index:1.617
Boiling Point:282.8 °C at 760 mmHg
PKA:0.89±0.10(Predicted)
Flash Point:124.8 °C
PSA：51.80000
Density:1.437 g/cm³
LogP:1.29340
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Soluble in dimethyl sulfoxide and methanol.
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:129.0093748
Heavy Atom Count:8
Complexity:77.7

Purity/Quality:

98% ^*data from raw suppliers

6-Chloro-2-pyrazinamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-41-22
Safety Statements: 26-36/37/39-60-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=C(C=N1)Cl)N
Uses 2-Chloro-6-aminopyrazine is a disubstituted pyrazine used in the preparation of A2B adenosine receptor antagonists and other biologically active compounds. 2-Amino-6-chloropyrazine is used in the preparation of A2B adenosine receptor antagonists and other biologically active compounds.

Technology Process of 2-Amino-6-chloropyrazine

There total 4 articles about 2-Amino-6-chloropyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 4774-14-5
2,6-dichloropyrazine

: 33332-28-4
2-amino-6-chloropyrazine

Guidance literature:: With ammonia; at 100 ℃; for 5h; Temperature;

Reference yield: 77.0%

: 355836-31-6
6-chloro-N-(4-methoxybenzyl)pyrazin-2-amine

: 33332-28-4
2-amino-6-chloropyrazine

Guidance literature:: In trifluoroacetic acid;

Reference yield:

: 6863-77-0
3-aminopyrazine 1-oxide

: 6863-73-6
3-chloropyrazin-2-amine

: 33332-29-5
2-amino-5-chloropyrazine

: 33332-28-4
2-amino-6-chloropyrazine

Guidance literature:: With trichlorophosphate; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;