3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester

Base Information

• Chemical Name: 3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester
• CAS No.: 14442-51-4
• Molecular Formula: C₂₀H₁₉NO₂
• Molecular Weight: 305.376
• Mol file: 14442-51-4.mol

Synonyms:3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester

Chemical Property of 3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester

There total 2 articles about 3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-cyanoacetate (105-56-6) + 1,3-Diphenylpropanone (102-04-5) → 3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester (14442-51-4)

Guidance literature:

Reference yield:

→ 3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester (14442-51-4)

Guidance literature:

1,3-Diphenyl-aceton, Cyanessigsaeure-aethylester;

Reference yield:

3-benzyl-2-cyano-4-phenyl-crotonic acid ethyl ester (14442-51-4) → 2,2-dibenzyl-succinic acid-anhydride (7465-47-6)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous ethanol

2: aqueous KOH

3: acetyl chloride

With potassium hydroxide; ethanol; acetyl chloride;

upstream raw materials:

ethyl 2-cyanoacetate

1,3-Diphenylpropanone

Downstream raw materials:

3-benzyl-2,3-dicyano-4-phenyl-butyric acid ethyl ester

3-benzyl-4-phenyl-crotonic acid amide

2,2-dibenzyl-succinic acid-anhydride

2,2-dibenzyl-succinic acid-4-methyl ester