Biperiden hydrochloride

Base Information

• Chemical Name: Biperiden hydrochloride
• CAS No.: 1235-82-1
• Molecular Formula: C21H29NO^.HCl
• Molecular Weight: 347.97
• European Community (EC) Number: 214-976-2
• NSC Number: 170950,84989
• UNII: K35N76CUHF
• DSSTox Substance ID: DTXSID2047856
• Wikidata: Q27126508
• NCI Thesaurus Code: C65264
• ChEMBL ID: CHEMBL1201035
• Mol file: 1235-82-1.mol

Synonyms:Akineton;alpha-Bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol;Biperiden;Biperiden Hydrochloride;Biperiden, 1R-(1 alpha,2 alpha(R*),4 alpha)-Isomer;Biperiden, 1S-(1 alpha,2 alpha(R*),4 alpha)-Isomer;Biperidene;Hydrochloride, Biperiden

Chemical Property of Biperiden hydrochloride

Chemical Property:

• Appearance/Colour: White, crystalline, odorless powder
• Vapor Pressure: 2.45E-09mmHg at 25°C
• Melting Point: 238°
• Boiling Point: 462.1 °C at 760 mmHg
• Flash Point: 224.5 °C
• PSA: 23.47000
• LogP: 4.70230
• Storage Temp.: Desiccate at +4°C
• Solubility.: DMSO: >20mg/mL
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 347.2015923
• Heavy Atom Count: 24
• Complexity: 422

Purity/Quality:

99% ^*data from raw suppliers

Biperiden hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-R22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O.Cl
• Recent ClinicalTrials: Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability
• Uses: Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. Antiparkinsonian;Anticholinergic A muscarinic receptor antagonist
• Therapeutic Function: Antiparkinsonian
• Clinical Use: Biperiden hydrochloride has all of the actions describedfor biperiden. The hydrochloride is used for tablets becauseit is better suited to this dosage form than is the lactate salt.As with the free base and the lactate salt, xerostomia (drynessof the mouth) and blurred vision may occur.