Coenzyme

Base Information

• Chemical Name: Coenzyme
• CAS No.: 45127-11-5
• Molecular Formula: C4H10O6S4
• Molecular Weight: 282.3786
• Hs Code.: 2930909165
• Mol file: 45127-11-5.mol

Synonyms:2,2'-Dithiodi-1-ethanesulfonicacid;2,2'-Dithiodiethanesulfonic acid;Bis(2-sulfoethyl)disulfide;Coenzyme M;

Chemical Property of Coenzyme

Chemical Property:

• Refractive Index: 1.637
• PSA: 176.10000
• Density: 1.769 g/cm³
• LogP: 2.30500

Purity/Quality:

99%, ^*data from raw suppliers

Mesna impurity D European Pharmacopoeia (EP) Reference Standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Coenzyme M can be used for F430 Biosynthesis and insertion.

Technology Process of Coenzyme

There total 7 articles about Coenzyme which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,2'-dithiobisethanesulfonyl chloride (98022-97-0) → 2,2’-dithio-bis-ethane sulfonate (45127-11-5)

Guidance literature:

With water; In acetonitrile; at 20 ℃; for 120h;

Reference yield:

1-mercaptoethanesulfonic acid → 2,2’-dithio-bis-ethane sulfonate (45127-11-5) + dimesna

Guidance literature:

In water;

Reference yield:

mesna (19767-45-4) → 2,2’-dithio-bis-ethane sulfonate (45127-11-5)

Guidance literature:

With dihydrogen peroxide;

DOI:10.1021/jo01282a001

upstream raw materials:

2-Mercaptoethanesulfonic acid

mesna

sodium 2-bromethanesulfonate

2,2'-dithiobisethanesulfonyl chloride

Refernces

• 1、 -. "Medicinal disulfide salts". Page/Page column 2. . Retrieved 2008/06/13.
• 2、 Dicks, Andrew P.,Li,Munro, Andrew P.,Swift, Helen R.,Williams, D. Lyn H.. "The reaction of S-nitrosothiols with thiols at high thiol concentration". . p. 789 - 794. Retrieved 2007/10/03.