2-[2-[[3,12-dihydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Base Information

• Chemical Name: 2-[2-[[3,12-dihydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS No.: 52286-58-5
• Molecular Formula: C₄₂H₇₂O₁₄
• Molecular Weight: 801.025
• Hs Code.: 29389090
• Wikidata: Q105282226
• Mol file: 52286-58-5.mol

Synonyms:Panaxoside RF;LS-15446

Chemical Property of 2-[2-[[3,12-dihydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 197～198℃
• Refractive Index: 1.601
• Boiling Point: 912.3 °C at 760 mmHg
• PKA: 12.85±0.70(Predicted)
• Flash Point: 505.5 °C
• PSA: 239.22000
• Density: 1.33 g/cm³
• LogP: 1.11980
• Storage Temp.: ?20°C
• Solubility.: Methanol (Slightly), Pyridine (Slightly)
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 10
• Exact Mass: 800.49220697
• Heavy Atom Count: 56
• Complexity: 1410

Purity/Quality:

95%-98% ^*data from raw suppliers

Ginsenoside Rf ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 2-45-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)O)C)O)C
• Uses: Ginsenoside Rf is an anti-arthritic agent, attenuating collagen-induced arthritis in mice.

Technology Process of 2-[2-[[3,12-dihydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

There total 1 articles about 2-[2-[[3,12-dihydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ C42H72O14 (52286-58-5,97276-51-2)

Guidance literature:

20-Glucoginsenosid, partielle Hydrolyse;

Reference yield: 90.4%

ginsenoside Rf (52286-58-5,97276-51-2) → 20S-protopanaxatriol (1453-93-6,34080-08-5,32773-56-1)

Guidance literature:

With Aspergillus niger β-glucosidase; water; at 55 ℃; for 16h; pH=5; pH-value; Temperature; Concentration; Time; stereoselective reaction; Kinetics; aq. acetate buffer; Enzymatic reaction;

DOI:10.1271/bbb.90596

Reference yield:

ginsenoside Rf (52286-58-5,97276-51-2) → β-D-glucose (492-61-5) + ginsenoside Rh1 (80952-71-2,63223-86-9)

Guidance literature:

With Penicillium decumbens naringinase; enzymatic hydrolysis;

DOI:10.1055/s-2003-38476

Downstream raw materials:

β-D-glucose

ginsenoside Rh₁

20S-protopanaxatriol