C₆₆H₇₉N₃O₈

Base Information

• Chemical Name: C₆₆H₇₉N₃O₈
• CAS No.: 947747-26-4
• Molecular Formula: C₆₆H₇₉N₃O₈
• Molecular Weight: 1042.37
• Mol file: 947747-26-4.mol

Synonyms:C₆₆H₇₉N₃O₈

Chemical Property of C₆₆H₇₉N₃O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₇₉N₃O₈

There total 25 articles about C₆₆H₇₉N₃O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(2S,3S,4R)-2-azido-3-benzyloxy-1-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyloxy)octadec-5-yn-4-ol (947747-25-3) + benzyl bromide (100-39-0) → C66H79N3O8 (947747-26-4)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2007.05.161

Reference yield:

C17H22O6 → C66H79N3O8 (947747-26-4)

Guidance literature:

Multi-step reaction with 11 steps

1: 90 percent / LiAlH₄ / tetrahydrofuran

2: 73 percent / NaH / tetrahydrofuran

3: 90 percent / BH₃*SMe₂; BF₃*OEt₂ / CH₂Cl₂

4: 96 percent / pyridine

5: 88 percent / pyridine

6: 94 percent / NaN₃ / dimethylformamide

7: 95 percent / TBAF / tetrahydrofuran

8: 94 percent / Dess-Martin periodinane; NaHCO₃ / CH₂Cl₂

9: 97 percent / BuLi / tetrahydrofuran

10: 90 percent / NaH / dimethylformamide

11: 55 percent / AgClO₄; SnCl₄; MS₄A / diethyl ether; CH₂Cl₂

With lithium aluminium tetrahydride; n-butyllithium; sodium azide; dimethylsulfide borane complex; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; silver perchlorate; tin(IV) chloride; sodium hydride; sodium hydrogencarbonate; Dess-Martin periodane; In tetrahydrofuran; pyridine; diethyl ether; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2007.05.161

Reference yield:

benzaldehyde dimethyl acetal (1125-88-8) → C66H79N3O8 (947747-26-4)

Guidance literature:

Multi-step reaction with 12 steps

1: 73 percent / p-TsOH*H₂O / toluene / Heating

2: 90 percent / LiAlH₄ / tetrahydrofuran

3: 73 percent / NaH / tetrahydrofuran

4: 90 percent / BH₃*SMe₂; BF₃*OEt₂ / CH₂Cl₂

5: 96 percent / pyridine

6: 88 percent / pyridine

7: 94 percent / NaN₃ / dimethylformamide

8: 95 percent / TBAF / tetrahydrofuran

9: 94 percent / Dess-Martin periodinane; NaHCO₃ / CH₂Cl₂

10: 97 percent / BuLi / tetrahydrofuran

11: 90 percent / NaH / dimethylformamide

12: 55 percent / AgClO₄; SnCl₄; MS₄A / diethyl ether; CH₂Cl₂

With lithium aluminium tetrahydride; n-butyllithium; sodium azide; dimethylsulfide borane complex; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; silver perchlorate; tin(IV) chloride; sodium hydride; sodium hydrogencarbonate; Dess-Martin periodane; toluene-4-sulfonic acid; In tetrahydrofuran; pyridine; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.tetlet.2007.05.161

upstream raw materials:

(2S,3S,4R)-2-azido-3-benzyloxy-1-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyloxy)octadec-5-yn-4-ol

benzyl bromide

C₄₂H₄₀O₅

C₄₃H₄₂O₇S

Refernces