2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide

Base Information

• Chemical Name: 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
• CAS No.: 141776-47-8
• Molecular Formula: C9H11N3O4S2
• Molecular Weight: 289.336
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID10573139
• Nikkaji Number: J1.640.912J
• Wikidata: Q72477229
• Mol file: 141776-47-8.mol

Synonyms:141776-47-8;2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide;2-(Ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide;2-(Ethylsulfonyl)-imidazo-[1,2-a]-pyridine-3-sulfonamide;Imidazo[1,2-a]pyridine-3-sulfonamide, 2-(ethylsulfonyl)-;2-(ethanesulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide;MFCD09743548;C9H11N3O4S2;ulfosulfuron TP1;MJVXHAPMFSPZRH-UHFFFAOYSA-N;ulfosulfuron sulfonamide;SCHEMBL8175596;2-(Ethylsulphonyl)imidazo[1,2-a]pyridine-3-sulphonamide;DTXSID10573139;AKOS015900641;CS-W003627;DS-2257;SY021281;NS00067748;A23914;2-ethylsulfonylimidazo{1,2-a}pyridin-3-sulfonamide;J-007555;2-(ethylsulfonyl)H-imidazo[1,2-a]pyridine-3-sulfonamide

Chemical Property of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide

Chemical Property:

• Appearance/Colour: White crystal
• Refractive Index: 1.706
• PKA: 5.40±0.60(Predicted)
• PSA: 128.36000
• Density: 1.67 g/cm³
• LogP: 2.63720
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 289.01909819
• Heavy Atom Count: 18
• Complexity: 505

Purity/Quality:

99% ^*data from raw suppliers

2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: Xi:刺激性物质

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)N
• Use Description: 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide is a compound with several applications in different fields. In the pharmaceutical industry, it can serve as a potential drug candidate or intermediate in the synthesis of pharmaceuticals due to its unique chemical structure. In the field of agricultural chemistry, it may find use in the development of crop protection agents or herbicides. Furthermore, this compound can be employed in chemical research as a building block for the synthesis of more complex molecules, making it valuable for the advancement of various scientific disciplines. Its versatility as a chemical compound highlights its potential in contributing to advancements across multiple fields of science and industry.

Technology Process of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide

There total 1 articles about 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethylthioimidazo[1,2-a]pyridine-3-sulfonamide → 2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide (141776-47-8)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In N-methyl-acetamide; water;

Reference yield: 74.0%

5-chloro-2,3-difluoropyridine (89402-43-7) + (R)-2-(4-hydroxyphenoxy)propionic acid (94050-90-5) + 2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide (141776-47-8) → (R)-2-ethanesulfonylimidazo[1,2-a]pyridine-3-sulfonic acid [2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionyl]amide (1361405-60-8)

Guidance literature:

5-chloro-2,3-difluoropyridine; (R)-2-(4-hydroxyphenoxy)propionic acid; With potassium phosphate; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 50 - 60 ℃; for 2h;

With 1,3,5-trichloro-2,4,6-triazine; In N,N-dimethyl-formamide; at 5 - 25 ℃; for 1.16667h;

2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide; In N,N-dimethyl-formamide;

DOI:10.4067/S0717-97072011000400002

Reference yield:

phenyl chloroformate (1885-14-9) + 2-ethylsulfonylimidazo[1,2a]pyridine-3-sulfonamide (141776-47-8) → C16H15N3O6S2 (905926-26-3)

Guidance literature:

With triethylamine; In acetonitrile; at 3 - 20 ℃;

DOI:10.1002/jlcr.934

Downstream raw materials:

C₁₆H₁₅N₃O₆S₂

(R)-2-ethanesulfonylimidazo[1,2-a]pyridine-3-sulfonic acid [2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionyl]amide

Refernces