C₅H₄NC₆H₄C₂ON₂C₆H₄N(C₆H₄CH₃)2

Base Information

• Chemical Name: C₅H₄NC₆H₄C₂ON₂C₆H₄N(C₆H₄CH₃)2
• CAS No.: 922495-47-4
• Molecular Formula: C₃₃H₂₆N₄O
• Molecular Weight: 494.596
• Mol file: 922495-47-4.mol

Synonyms:C₅H₄NC₆H₄C₂ON₂C₆H₄N(C₆H₄CH₃)2

Chemical Property of C₅H₄NC₆H₄C₂ON₂C₆H₄N(C₆H₄CH₃)2

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅H₄NC₆H₄C₂ON₂C₆H₄N(C₆H₄CH₃)2

There total 7 articles about C₅H₄NC₆H₄C₂ON₂C₆H₄N(C₆H₄CH₃)2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C28H22BrN3O (922495-44-1) + 2-tri-n-butylstannylpyridine (17997-47-6) → C5H4NC6H4C2ON2C6H4N(C6H4CH3)2 (922495-47-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 110 ℃; for 50h; Inert atmosphere;

DOI:10.1016/j.dyepig.2010.08.001

Reference yield:

4-(2H-tetrazol-5-yl)phenyl-di(4-tolyl)amine (922495-41-8) → C5H4NC6H4C2ON2C6H4N(C6H4CH3)2 (922495-47-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 48 h / Inert atmosphere; Reflux

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 50 h / 110 °C / Inert atmosphere

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; 2: Stille coupling;

DOI:10.1016/j.dyepig.2010.08.001

Reference yield:

N-phenyl-di-p-tolylamine (20440-95-3) → C5H4NC6H4C2ON2C6H4N(C6H4CH3)2 (922495-47-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: trichlorophosphate / 48 h / 0 - 120 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere; Cooling with ice

2.1: pyridine; hydroxylamine hydrochloride; acetic acid / N,N-dimethyl-formamide / 9 h / 130 °C / Inert atmosphere

3.1: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 90 h / Inert atmosphere; Reflux

4.1: pyridine / 48 h / Inert atmosphere; Reflux

5.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 50 h / 110 °C / Inert atmosphere

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium azide; hydroxylamine hydrochloride; ammonium chloride; acetic acid; trichlorophosphate; In N,N-dimethyl-formamide; toluene; 5.1: Stille coupling;

DOI:10.1016/j.dyepig.2010.08.001

upstream raw materials:

4-(2H-tetrazol-5-yl)phenyl-di(4-tolyl)amine

C₂₈H₂₂BrN₃O

2-tri-n-butylstannylpyridine

4-tolyl iodide

Downstream raw materials:

Pt(CH₃COCHCOCH₃)(C₅H₄NC₆H₃C₂ON₂C₆H₄N(C₆H₄CH₃)2)

Refernces