2-Amino-6-chloro-4-nitrophenol

Base Information

• Chemical Name: 2-Amino-6-chloro-4-nitrophenol
• CAS No.: 6358-09-4
• Molecular Formula: C6H5ClN2O3
• Molecular Weight: 188.57
• Hs Code.: 29225090
• European Community (EC) Number: 228-762-1,263-645-9
• UNII: 0ZLP5I1TMC
• DSSTox Substance ID: DTXSID9043855
• Nikkaji Number: J81.202A
• Wikidata: Q27251077
• Mol file: 6358-09-4.mol

Synonyms:6-chloro-4-nitro-2-aminophenol;6-chloro-4-nitro-2-aminophenol, monohydrochloride

Chemical Property of 2-Amino-6-chloro-4-nitrophenol

Chemical Property:

• Appearance/Colour: Dull yellow to brown powder
• Vapor Pressure: 0.002Pa at 32℃
• Melting Point: 158-162.5 °C
• Boiling Point: 358.7 °C at 760 mmHg
• PKA: 5.20±0.44(Predicted)
• Flash Point: 170.8 °C
• PSA: 92.07000
• Density: 1.655 g/cm³
• LogP: 2.64040
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility.: 450mg/L at 25℃
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 187.9988697
• Heavy Atom Count: 12
• Complexity: 184

Purity/Quality:

98%, ^*data from raw suppliers

2-Amino-6-chloro-4-nitrophenol >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1N)O)Cl)[N+](=O)[O-]
• Uses: 2-Amino-6-chloro-4-nitrophenol has cosmetic application in hair dye compositions.

Technology Process of 2-Amino-6-chloro-4-nitrophenol

There total 6 articles about 2-Amino-6-chloro-4-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-4,6-dinitro-phenol (946-31-6) → 2-amino-6-chloro-4-nitrophenol (6358-09-4)

Guidance literature:

With iron sulfide; sodium sulfide; water;

Reference yield:

2-monochlorophenol (95-57-8) → 2-amino-6-chloro-4-nitrophenol (6358-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: nitric acid

2: ammonium sulfide

With ammonium sulfide; nitric acid;

DOI:10.1359/jbmr.2001.16.3.478

Reference yield:

2-chloro-4-nitrophenol (619-08-9) → 2-amino-6-chloro-4-nitrophenol (6358-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: nitric acid

2: ammonium sulfide

With ammonium sulfide; nitric acid;

DOI:10.1359/jbmr.2001.16.3.478

upstream raw materials:

2-chloro-4,6-dinitro-phenol

2-monochlorophenol

2-chloro-4-nitrophenol

2-chloro-6-nitrophenol

Downstream raw materials:

6-chloro-4-nitro-1,2-quinone-2-diazide

phenol

(3-Chlor-2-hydroxy-5-nitro-phenylazo)-acetoacetanilid