4'-Amino-3',5'-dichloroacetophenone

Base Information Edit

Chemical Name:4'-Amino-3',5'-dichloroacetophenone
CAS No.:37148-48-4
Molecular Formula:C8H7Cl2NO
Molecular Weight:204.056
Hs Code.:29223990
European Community (EC) Number:253-368-1
UNII:EC3RI6O2DB
DSSTox Substance ID:DTXSID70190629
Nikkaji Number:J260.746H
Wikidata:Q72435648
Mol file:37148-48-4.mol

Synonyms:37148-48-4;4'-Amino-3',5'-dichloroacetophenone;4-Amino-3,5-dichloroacetophenone;1-(4-Amino-3,5-dichlorophenyl)ethanone;1-(4-Amino-3,5-dichlorophenyl)ethan-1-one;3,5-Dichloro-4-aminoacetophenone;Ethanone, 1-(4-amino-3,5-dichlorophenyl)-;4-acetyl-2,6-dichloroaniline;1-(4-Amino-3,5-dichlorophenyl)-ethanone;EC3RI6O2DB;EINECS 253-368-1;MFCD00238535;1-(4-AMINO-3,5-DICHLORO-PHENYL)-2-ETHANONE;UNII-EC3RI6O2DB;Clenbuterol EP Impurity C;SCHEMBL2866567;DTXSID70190629;BCP30576;STL414858;3',5'-Dichloro-4'-Aminoacetophenone;4`-Amino-3`,5`-dichloroacetophenone;AKOS005169258;AC-7309;CS-T-02385;CS-W005483;SB78425;AS-62139;SY005676;1-(4-amino-3,5-dichloro-phenyl)-ethanone;1-(4-Amino-3,5-dichlorophenyl)ethanone #;4'-Amino-3',5'-dichloroacetophenone, 97%;AM20060611;FT-0617478;1-(4-Amino-3,5-dichlorophenyl)-2-ethanone;EN300-117586;W-106567;Clenbuterol Impurity C;4 inverted exclamation mark -Amino-3 inverted exclamation mark ,5 inverted exclamation mark -dichloroacetophenone

Suppliers and Price of 4'-Amino-3',5'-dichloroacetophenone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Amino-3,5-dichlorophenyl)-2-ethanone
10g
$ 230.00

TCI Chemical
4'-Amino-3',5'-dichloroacetophenone >98.0%(GC)
25g
$ 174.00

TCI Chemical
4'-Amino-3',5'-dichloroacetophenone >98.0%(GC)
5g
$ 60.00

SynQuest Laboratories
4'-Amino-3',5'-dichloroacetophenone
100 g
$ 464.00

Sigma-Aldrich
4′-Amino-3′,5′-dichloroacetophenone 97%
25g
$ 189.00

Medical Isotopes, Inc.
1-(4-Amino-3,5-dichloro-phenyl)-2-ethanone
1 g
$ 190.00

Matrix Scientific
4'-Amino-3',5'-dichloroacetophenone 95+%
1g
$ 36.00

Matrix Scientific
4'-Amino-3',5'-dichloroacetophenone 95+%
5g
$ 91.00

Matrix Scientific
4'-Amino-3',5'-dichloroacetophenone 95+%
10g
$ 135.00

Frontier Specialty Chemicals
4-Amino-3,5-dichloroacetophenone 98%
25g
$ 156.00

Total 179 raw suppliers

Chemical Property of 4'-Amino-3',5'-dichloroacetophenone Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:4.1E-05mmHg at 25°C
Melting Point:162-166 °C(lit.)
Refractive Index:1.599
Boiling Point:351.5 °C at 760 mmHg
PKA:-1.72±0.10(Predicted)
Flash Point:166.4 °C
PSA：43.09000
Density:1.386 g/cm³
LogP:3.35940
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:202.9904692
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

1-(4-Amino-3,5-dichlorophenyl)-2-ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C(=C1)Cl)N)Cl
Description 4-Amino-3,5-dichloroacetophenone is an intermediate in the synthesis of the antitussive and antiasthmatic drug gramtin.
Uses 4-Amino-3,5-dichloroacetophenone is used to synthesize the drug Clenbuterol. Clenbuterol is a steroid-like chemical that was initially developed to treat asthma in horses, working by relaxing the airways in the animals'lungs.

Technology Process of 4'-Amino-3',5'-dichloroacetophenone

There total 5 articles about 4'-Amino-3',5'-dichloroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.9%