uridylyl-(2'->5')-uridine

Base Information

• Chemical Name: uridylyl-(2'->5')-uridine
• CAS No.: 13493-13-5
• Molecular Formula: C₁₈H₂₃N₄O₁₄P
• Molecular Weight: 550.373
• Mol file: 13493-13-5.mol

Synonyms:uridylyl-(2'->5')-uridine

Chemical Property of uridylyl-(2'->5')-uridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of uridylyl-(2'->5')-uridine

There total 7 articles about uridylyl-(2'->5')-uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

uridylyl-3',5'-uridine (2415-43-2) → uridine 2',3'-cyclic phosphate (606-02-0) + uridylyl-(2'->5')-uridine (13493-13-5) + uridine (58-96-8)

Guidance literature:

With morpholine; morpholin hydrochloride; sodium chloride; at 80 ℃; Rate constant; Mechanism; μ = 0.2 M, var. morpholine buffer conc. and morpholine/HCl ratios;

DOI:10.1021/ja00076a031

Reference yield:

UTP (63-39-8) → U2'p5'U2'p5'U (22566-84-3) + uridylyl-(2'->5')-uridine (13493-13-5) + uridine (58-96-8)

Guidance literature:

UTP; With potassium chloride; magnesium chloride; at 37 ℃; for 20h; pH=8; aq. buffer; Enzymatic reaction;

With shrimp alkaline phosphatase; magnesium chloride; at 37 ℃; for 1h; pH=8; aq. buffer; Enzymatic reaction;

DOI:10.3390/md8020235

Reference yield:

uridylyl-3',5'-uridine (2415-43-2) → uridine 2',3'-cyclic phosphate (606-02-0) + uridine-3'-phosphate (84-53-7) + uridine 2'-monophosphate (131-83-9) + uridylyl-(2'->5')-uridine (13493-13-5) + uridine (58-96-8)

Guidance literature:

With sodium perchlorate; In dimethyl sulfoxide; at 90 ℃; Solvent; Kinetics; Sealed tube;

DOI:10.1039/c4ob02682a

upstream raw materials:

uridylyl-3',5'-uridine

(S_P)-uridylyl(3',5')uridine phosphoromonothioate

(R_P)-uridylyl(3',5')uridine phosphoromonothioate

UTP

Downstream raw materials:

uridine 2'-monophosphate

uridine

uridylyl-3',5'-uridine

Refernces

• 1、 Breslow, Ronald,Xu, Ruo. "Quantitative evidence for the mechanism of RNA cleavage by enzyme mimics. Cleavage and isomerization of UpU by morpholine buffers". . p. 10705 - 10713. Retrieved 1993.
• 2、 Breslow, Ronald,Dong, Steven D.,Webb, Yael,Xu, Ruo. "Further studies on the buffer-catalyzed cleavage and isomerization of uridyluridine. Medium and ionic strength effects on catalysis by morpholine, imidazole, and acetate buffers help clarify the mechanisms involved and their relationship to the mechanism used by the enzyme ribonuclease and by a ribonuclease mimic". . p. 6588 - 6600. Retrieved 1996.
• 3、 Lopp, Annika,Reintamm, Tonu,Kuusksalu, Anne,Tammiste, Indrek,Pihlak, Arno,Kelve, Merike. "Natural occurrence of 2′,5′-linked heteronucleotides in marine sponges". experimental part. p. 235 - 254. Retrieved 2010/10/19.