3,3′,4′,7-tetraacetoxyflavone

Base Information

• Chemical Name: 3,3′,4′,7-tetraacetoxyflavone
• CAS No.: 114840-33-4
• Molecular Formula: C₂₃H₁₈O₁₀
• Molecular Weight: 454.39
• Mol file: 114840-33-4.mol

Synonyms:3,3′,4′,7-tetraacetoxyflavone

Chemical Property of 3,3′,4′,7-tetraacetoxyflavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3′,4′,7-tetraacetoxyflavone

There total 6 articles about 3,3′,4′,7-tetraacetoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,3′,4′,7-tetraacetoxy-5-triuoromethylsufonyloxyflavone → 3,3′,4′,7-tetraacetoxyflavone (114840-33-4)

Guidance literature:

With Pd(OH)2/C, 20%; hydrogen; triethylamine; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1080/09168451.2018.1467263

Reference yield:

quercetol (117-39-5,74893-81-5) → 3,3′,4′,7-tetraacetoxyflavone (114840-33-4)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / 3 h / 80 °C

2: boron trifluoride diethyl etherate / 1,4-dioxane / 6 h / 80 °C

3: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

4: Pd(OH)2/C, 20%; triethylamine; hydrogen / tetrahydrofuran / 1 h / 20 °C

With pyridine; 2,6-dimethylpyridine; Pd(OH)2/C, 20%; boron trifluoride diethyl etherate; hydrogen; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane;

DOI:10.1080/09168451.2018.1467263

Reference yield:

3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one (1064-06-8) → 3,3′,4′,7-tetraacetoxyflavone (114840-33-4)

Guidance literature:

Multi-step reaction with 3 steps

1: boron trifluoride diethyl etherate / 1,4-dioxane / 6 h / 80 °C

2: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

3: Pd(OH)2/C, 20%; triethylamine; hydrogen / tetrahydrofuran / 1 h / 20 °C

With 2,6-dimethylpyridine; Pd(OH)2/C, 20%; boron trifluoride diethyl etherate; hydrogen; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane;

DOI:10.1080/09168451.2018.1467263

upstream raw materials:

3,7,3',4'-tetrahydroxyflavone

acetic anhydride

quercetol

3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one

Downstream raw materials:

3,7,3',4'-tetrahydroxyflavone

Refernces

• 1、 Bezuidenhout, S. Catherine,Bezuidenhoudt, Barend C. B.,Ferreira, Daneel. "α-HYDROXYDIHYDROCHALCONES AND RELATED 1,3-DIARYLPROPAN-2-ONES FROM XANTHOCERCIS ZAMBESIACA". . p. 2329 - 2334. Retrieved 2007/10/02.