trans-4-Pentylcyclohexanecarboxylic acid

Base Information

• Chemical Name: trans-4-Pentylcyclohexanecarboxylic acid
• CAS No.: 38289-29-1
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.305
• Hs Code.: 29162090
• Mol file: 38289-29-1.mol

Synonyms:TRANS-4-N-AMYLCYCLOHEXANECARBOXYLIC ACID;TRANS-4-N-PENTYLCYCLOHEXANECARBOXYLIC ACID;TRANS-4-PENTYLCYCLOHEXANECARBOXYLIC ACID;ZLI-1153;4-trans-pentyl-cyclohexane carboxylic acid;Trans-4-PentylcyclohexaneCarboxylicAcid,5HaC12H22O2;trans-4-n-Pentylcyclohexanecarboxylicacid,98%;trans-4-amylcyclohexanecarboxylic acid

Chemical Property of trans-4-Pentylcyclohexanecarboxylic acid

Chemical Property:

• Appearance/Colour: white fine crystalline powder
• Vapor Pressure: 0.000198mmHg at 25°C
• Melting Point: 51-53 °C(lit.)
• Refractive Index: 1.466
• Boiling Point: 304.6 °C at 760 mmHg
• PKA: 4.94±0.10(Predicted)
• Flash Point: 147.4 °C
• PSA: 37.30000
• Density: 0.963 g/cm³
• LogP: 3.45770
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: almost transparency in Methanol

Purity/Quality:

99%, ^*data from raw suppliers

trans-4-Pentylcyclohexanecarboxylic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: trans-4-Pentylcyclohexanecarboxylic acid has been used in preparation of:4-[(2-(trans-4-pentylcyclohexyl)ethyl]phenol4-[(4-trans-pentyl-cyclohexanecarbonyl)-(4-pyridin-4-yl-benzyl)-amino]-piperidine-1-tert-butyl carbamate2-cyano-1-benzofuran-5-yl trans-4-pentylcyclohexanecarboxylate Intermediates of Liquid Crystals

Technology Process of trans-4-Pentylcyclohexanecarboxylic acid

There total 2 articles about trans-4-Pentylcyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-pentylbenzoic acid (26311-45-5) → 4-trans-pentylcyclohexane-1-carboxylic acid (38289-29-1,38792-89-1,67589-84-8)

Guidance literature:

4-pentylbenzoic acid; With sodium hydroxide; hydrogen; In water; at 140 - 150 ℃; for 1h; under 22502.3 - 30003 Torr;

With sodium hydroxide; In water; at 260 - 280 ℃; for 2h; under 22502.3 - 30003 Torr; Further stages.;

DOI:10.1016/j.tetlet.2004.06.117

Reference yield:

→ 4-trans-pentylcyclohexane-1-carboxylic acid (38289-29-1,38792-89-1,67589-84-8)

Guidance literature:

4-Pentylbenzoesaeure, 1) H2/Raney-Ni (Bildung cis- u. trans-Cyclohexansaeure), 2) Thioharnstoff (Bildung trans-Saeure-Einschlussverb.), 3) HCl;

Reference yield: 100.0%

4-trans-pentylcyclohexane-1-carboxylic acid (38289-29-1,38792-89-1,67589-84-8) → trans-4-pentylcyclohexane-1-carboxylic acid chloride (67589-90-6)

Guidance literature:

With thionyl chloride;

upstream raw materials:

4-pentylbenzoic acid

Downstream raw materials:

(R)-Benzyl 2-<4-(trans-4-pentylcyclohexylcarbonyloxy)phenoxy>propanoate

trans-4-pentylcyclohexanecarboxamide

trans-4-bromomethyl-1-n-pentylcyclohexane

trans-4-pentylcyclohexane-1-carboxylic acid chloride

Refernces

• 1、 -. "Long-acting androgenic compounds and pharmaceutical compositions thereof". . . Retrieved 2008/06/13.