Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester

Base Information

• Chemical Name: Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester
• CAS No.: 173677-12-8
• Molecular Formula: C₃₄H₄₉NO₆
• Molecular Weight: 567.766
• Mol file: 173677-12-8.mol

Synonyms:Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester

Chemical Property of Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester

There total 3 articles about Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acryloyl chloride (814-68-6,25189-84-8) + 11-[(R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecan-1-ol (173677-09-3) → Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester (173677-12-8)

Guidance literature:

With 2-hydroxyresorcinol; In benzene; at 40 ℃; for 1h;

DOI:10.1021/jm950477z

Reference yield:

1-Bromo-11-hydroxyundecane (1611-56-9) → Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester (173677-12-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / acetonitrile / 70 h / Heating

2: 99 percent / pyrogallol / benzene / 1 h / 40 °C

With 2-hydroxyresorcinol; In acetonitrile; benzene;

DOI:10.1021/jm950477z

Reference yield:

(-) N-norlaudanosine (50896-90-7) → Acrylic acid 11-[(R)-1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecyl ester (173677-12-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / acetonitrile / 70 h / Heating

2: 99 percent / pyrogallol / benzene / 1 h / 40 °C

With 2-hydroxyresorcinol; In acetonitrile; benzene;

DOI:10.1021/jm950477z

upstream raw materials:

acryloyl chloride

11-[(R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-undecan-1-ol

1-Bromo-11-hydroxyundecane

(-) N-norlaudanosine

Refernces