Notoginseng triterpenes

Base Information

• Chemical Name: Notoginseng triterpenes
• CAS No.: 88105-29-7
• Molecular Formula: C₄₇H₈₀O₁₇
• Molecular Weight: 917.142
• Mol file: 88105-29-7.mol

Synonyms:Dammarane,b-D-glucopyranoside deriv.;Ginsenoside Mb; Notoginsenoside Fe

Chemical Property of Notoginseng triterpenes

Chemical Property:

• Boiling Point: 994.1±65.0 °C(Predicted)
• PKA: 12.91±0.70(Predicted)
• PSA: 277.91000
• Density: 1.36±0.1 g/cm3(Predicted)
• LogP: 0.61230

Purity/Quality:

99% ^*data from raw suppliers

Notoginsenoside Fe ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Notoginseng triterpenes (NTs) are the active components extracted from Panax notoginseng, reducing oxygen consumption and improving the body’s tolerance to hypoxia. However, their role in random flap survival has not been elucidated. In this study, we used a mouse random skin flap model to verify that NT can promote cell proliferation and migration and that increasing blood perfusion can effectively improve the survival area of a skin flap.
• Uses: Notoginsenoside Fe is medicinal herb from Panax ginseng which exert immunomodulatory and anti-inflammatory activities.

Technology Process of Notoginseng triterpenes

There total 2 articles about Notoginseng triterpenes which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

ginsenoside Rc → notoginsenoside Fe (88105-29-7)

Guidance literature:

With Sphingopyxis sp. BG₉₇;

DOI:10.1007/s10600-014-1019-4

Reference yield:

ginsenoside Rc → 3-O-β-D-glucopyranosyl-20-O-[alpha-L-arabinofuranosyl(1->6)-β-D-glucopyranosyl]-20(S)-protopanaxadiol (88105-29-7)

Guidance literature:

With recombinant β-glycosidase from Microbacterium sp. Gsoil 167, Ile184Ala, Ile389Ala, Phe390Ala mutant; for 1h; Reagent/catalyst; Enzymatic reaction;

DOI:10.1002/cbic.201500004

Refernces

• 1、 Kim, Yeong-Su,Kim, Do-Yeon,Kang, Dong Wook,Park, Chang-Su. "Hydrolysis of the outer β-(1,2)-d-glucose linkage at the C-3 position of ginsenosides by a commercial β-galactosidase and its use in the production of minor ginsenosides". supporting information. . Retrieved 2018/07/30.
• 2、 Park, Sang Jin,Choi, Jung Min,Kyeong, Hyun-Ho,Kim, Song-Gun,Kim, Hak-Sung. "Rational design of a β-glycosidase with high regiospecificity for triterpenoid tailoring". . p. 854 - 860. Retrieved 2015/03/30.