Apramycin sulfate

Base Information

• Chemical Name: Apramycin sulfate
• CAS No.: 65710-07-8
• Molecular Formula: C₂₁H₄₁N₅O₁₁*H₂O₄S
• Molecular Weight: 637.663
• Hs Code.: 29419000
• European Community (EC) Number: 265-890-7,687-974-6
• UNII: 8UYL6NAZ3Q
• NCI Thesaurus Code: C79973
• Mol file: 65710-07-8.mol

Synonyms:apramycin;apramycin sulfate;EBL-1003

Chemical Property of Apramycin sulfate

Chemical Property:

• Appearance/Colour: powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: >168oC (dec.)
• Boiling Point: 823 °C at 760 mmHg
• Flash Point: 451.6 °C
• PSA: 41.99000
• Density: 1.56
• LogP: 3.82570
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble25mg/mL
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 13
• Hydrogen Bond Acceptor Count: 20
• Rotatable Bond Count: 6
• Exact Mass: 637.24763686
• Heavy Atom Count: 42
• Complexity: 841

Purity/Quality:

99% ^*data from raw suppliers

Apramycin sulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,Xn
• Hazard Codes: T,Xn
• Statements: 61-35-36/37/38-20/21/22-36/38
• Safety Statements: 53-26-36/37/39-45-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1C(C2C(CC(C(O2)OC3C(CC(C(C3O)O)N)N)N)OC1OC4C(C(C(C(O4)CO)N)O)O)O.OS(=O)(=O)O
• Isomeric SMILES: CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O.OS(=O)(=O)O
• Uses: antibacterial; LD50(iv) 280mg/kg(mouse) Apramycin sulfate binds to the deep groove of RNA and effectively inhibits ribosomal translocation prohibiting protein synthesis. Apramycin sulfate is a broad spectrum aminocyclitol antibiotic and component of the Nebramycin complex, produced by a strain of Streptomyces tenebrarius. Antibacterial.