Phorate

Base Information Edit

Chemical Name:Phorate
CAS No.:298-02-2
Molecular Formula:C7H17O2PS3
Molecular Weight:260.383
Hs Code.:
European Community (EC) Number:206-052-2
ICSC Number:1060
UN Number:3018
UNII:3W54X3W9IV
DSSTox Substance ID:DTXSID4032459
Nikkaji Number:J5.462C
Wikipedia:Phorate
Wikidata:Q421197
NCI Thesaurus Code:C163687
Metabolomics Workbench ID:56000
ChEMBL ID:CHEMBL510014
Mol file:298-02-2.mol

Synonyms:Phorate;Thimet 10 G;Thimet 10-G;Thimet 10G

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Chemical Property of Phorate Edit

Chemical Property:

Appearance/Colour:liquid
Vapor Pressure:0.0026mmHg at 25°C
Melting Point:-43 ºC
Refractive Index:1.54
Boiling Point:296 °C at 760 mmHg
Flash Point:132.8 °C
PSA：110.96000
Density:1.201 g/cm³
LogP:4.37830
Storage Temp.:0-6°C
Water Solubility.:0.005 g/100 mL
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:260.01283030
Heavy Atom Count:13
Complexity:156
Transport DOT Label:Poison

Purity/Quality:

Safty Information:

Pictogram(s): N; T+
Hazard Codes:T+;N,N,T+
Statements: 27/28-50/53-26/27/28
Safety Statements: 28-36/37-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Pesticides -> Organophosphate Insecticides
Canonical SMILES:CCOP(=S)(OCC)SCSCC
Inhalation Risk:A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20 °C; on spraying or dispersing, however, much faster.
Effects of Short Term Exposure:The substance may cause effects on the central nervous system. This may result in cholinesterase inhibition. Exposure could cause death. Medical observation is indicated. The effects may be delayed.
Effects of Long Term Exposure:Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Description Phorate is a kind of widely used organophosphate pesticide and acaricide1-2. It is a powerful pesticide effective against insects, mites, and nematodes3. It is a systemic insecticide that acts by inhibiting cholinesterases, enzymes involved in transmitting nerve impulses. However, it is very toxic both for target organisms and for mammals including human1-2. Because of its persistence in soil it is most useful in controlling soil-dwelling nematodes (microscopic roundworms that suck plant roots and transmit disease thereby). It is not recommended for use by the homeowner because it is extremely toxic and persistent3. Phorate is a colorless oil. The water solubility is 50 mg/L (25 ?C). It is miscible with common organic solvents. Log Kow = 3.92. Phorate is relatively unstable to hydrolysis in aqueous media; DT50 values at pH 7 and 9 are 3.2 and 3.9 d, respectively. Phorate is effective against sucking plant pests as a systemic insecticide-acaricide and also has good contact and vapor actions. It is usually formulated as granules. The acute oral LD50 for rats is 1.6–3.7 mg/kg. Inhalation LC50 (1 h) for rats is 0.06–0.011 mg/L air. ADI is 0.5 μg/kg b.w.
Uses Phorate is a non-biocumulative organophosphate used as an insecticide and acaricide. Phorate is an inhibitor of acetylcholinesterase and pseudocholinesterase. Insecticide. Phorate is a systemic insecticide used to control sucking and chewing pests in a very wide range of crops. It is also active as a nematicide and has some vapour phase activity. Systemic insecticide for control of mites, chewing and sucking insects in fruits and vegetables, cotton and some ornamentals

Technology Process of Phorate

There total 3 articles about Phorate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: