Levofloxacin hydrochloride

Base Information

• Chemical Name: Levofloxacin hydrochloride
• CAS No.: 177325-13-2
• Molecular Formula: C18H20FN3O4^.HCl
• Molecular Weight: 397.83
• Hs Code.: 29349990
• European Community (EC) Number: 604-067-2,605-797-4
• UNII: HTN0D03VRZ
• DSSTox Substance ID: DTXSID80432709
• Wikidata: Q27280093
• ChEMBL ID: CHEMBL2237108
• Mol file: 177325-13-2.mol

Synonyms:Levofloxacin hydrochloride;177325-13-2;Weilisu;Levofloxacin (hydrochloride);UNII-HTN0D03VRZ;HTN0D03VRZ;(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride;(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;hydrochloride;7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (S)-;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-;C18H21ClFN3O4;LEVOFLOXACIN HCL;Levofloxacinhydrochloride;138199-71-0;SCHEMBL554426;Levofloxacin Hydrochloride,(S);S-(-)-Ofloxacin hydrochloride;CHEMBL2237108;HY-B0330B;DTXSID80432709;AMY22188;BCP24629;Levofloxacin Hydrochloride Impurity A;MFCD03265511;AKOS007930523;AKOS015896241;AC-7617;2254176-11-7;AS-16117;LEVOFLOXACIN HYDROCHLORIDE [WHO-DD];CS-0014296;D78064;EN300-19833640;J-011269;Q27280093;(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid hydrochloride;(3S)-7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid,9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-,HCl;(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride

Chemical Property of Levofloxacin hydrochloride

Chemical Property:

• Vapor Pressure: 6.7E-14mmHg at 25°C
• Boiling Point: 571.5 °C at 760 mmHg
• Flash Point: 299.4 °C
• PSA: 75.01000
• LogP: 2.34890
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 397.1204620
• Heavy Atom Count: 27
• Complexity: 634

Purity/Quality:

99% ^*data from raw suppliers

LevofloxacinHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl
• Isomeric SMILES: C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl
• Recent EU Clinical Trials: A Randomized, Double-Blinded, Adaptive Phase 2 Study to Evaluate the Safety and Efficacy of IV or IV/PO Omadacycline and IV/PO Levofloxacin in the Treatment of Adults with Acute Pyelonephritis
• Uses: Levofloxacin Hydrochloride is a fluoroquinolone broad spectrum antibiotic. It is an inhibitor of two enzymes, DNA gyrase and topoisomerase IV.