1,2-Dichloro-3-(chloromethyl)benzene

Base Information

• Chemical Name: 1,2-Dichloro-3-(chloromethyl)benzene
• CAS No.: 3290-01-5
• Molecular Formula: C7H5Cl3
• Molecular Weight: 195.476
• Hs Code.: 2903999090
• European Community (EC) Number: 254-102-7,221-947-8
• UNII: B40AZJ572L
• DSSTox Substance ID: DTXSID40954553
• Nikkaji Number: J91.325A
• Wikidata: Q27274326
• Mol file: 3290-01-5.mol

Synonyms:2,3-Dichlorobenzyl chloride;1,2-Dichloro-3-(chloromethyl)benzene;3290-01-5;Benzene, dichloro(chloromethyl)-;DICHLOROBENZYL CHLORIDE;alpha,2,3-Trichlorotoluene;38721-71-0;2,3-dichloro-1-(chloromethyl)benzene;2,3-dichlorobenzylchloride;UNII-6Q4QCU6N2R;B40AZJ572L;HSDB 6167;Toluene, alpha, ar, ar-trichloro-;EINECS 254-102-7;NSC 30678;Benzene, 1,2-dichloro-3-(chloromethyl)-;dichloro-benzylchloride;6Q4QCU6N2R;UNII-B40AZJ572L;SCHEMBL283449;DTXSID40954553;EINECS 221-947-8;MFCD00035817;AKOS000261864;2,3-dichlorobenzyl chloride, AldrichCPR;1,2-Dichloro-3-(chloromethyl)benzene #;BS-44022;TOLUENE, .ALPHA.,2,3-TRICHLORO-;1,2-bis(chloranyl)-3-(chloromethyl)benzene;D2060;FT-0609562;D89987;EN300-183329;A821507;W-106807;Q27274326

Chemical Property of 1,2-Dichloro-3-(chloromethyl)benzene

Chemical Property:

• Appearance/Colour: Clear colorless liquid
• Vapor Pressure: 0.0336mmHg at 25°C
• Refractive Index: 1.578-1.58
• Boiling Point: 250.809 °C at 760 mmHg
• Flash Point: 160.158 °C
• PSA: 0.00000
• Density: 1.386 g/cm³
• LogP: 3.73220
• Water Solubility.: insoluble
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 193.945683
• Heavy Atom Count: 10
• Complexity: 105

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dichlorobenzyl Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-22
• Safety Statements: 45-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Halogenated Monoaromatics
• Canonical SMILES: C1=CC(=C(C(=C1)Cl)Cl)CCl
• Uses: 2,3-Dichlorobenzyl chloride is used in preparation of Biquaternary Ammonium compound. Also, used in preparation of of substituted Aryl- and Heteroarylcarboxylic Acid Hydrazides and salts thereof which are used to increase stress tolerance in plants.

Technology Process of 1,2-Dichloro-3-(chloromethyl)benzene

There total 5 articles about 1,2-Dichloro-3-(chloromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

antimonypentachloride (7647-18-9) + benzyl chloride (100-44-7) → 1-Chloro-4-(chloromethyl)benzene (104-83-6) + 1-chloro-2-(chloromethyl)benzene (611-19-8) + 2,3-dichlorobenzyl chloride (3290-01-5)

Guidance literature:

Chlorierung;

Reference yield:

2,3-dichlorobenzyl alcohol (38594-42-2) → 2,3-dichlorobenzyl chloride (3290-01-5)

Guidance literature:

With thionyl chloride; In benzene; Heating;

DOI:10.1021/jm00136a006

Reference yield:

2,3-dichloroaniline (608-27-5) → 2,3-dichlorobenzyl chloride (3290-01-5)

Guidance literature:

Multi-step reaction with 3 steps

2: NaBH₄ / methanol

3: SOCl₂ / benzene / Heating

With sodium tetrahydroborate; thionyl chloride; In methanol; benzene;

DOI:10.1021/jm00136a006

upstream raw materials:

2,3-dichlorobenzyl alcohol

antimonypentachloride

benzyl chloride

2,3-dichloroaniline

Downstream raw materials:

4-Chlor-2-(2,3-dichlor-benzyl)-phenol

(2,3-dichlorobenzyl)zinc(II) chloride

ethyl 1-(2,3-dichlorobenzyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

Refernces

• 1、 -. "Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones". . . Retrieved 2008/06/13.