C₃₇H₄₂N₆O₇

Base Information

• Chemical Name: C₃₇H₄₂N₆O₇
• CAS No.: 1252806-22-6
• Molecular Formula: C₃₇H₄₂N₆O₇
• Molecular Weight: 682.776
• Mol file: 1252806-22-6.mol

Synonyms:C₃₇H₄₂N₆O₇

Chemical Property of C₃₇H₄₂N₆O₇

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₃₇H₄₂N₆O₇

There total 3 articles about C₃₇H₄₂N₆O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

C17H20N2O5 (1252806-39-5) + (1-azidomethyl-2-methyl-propyl)-carbamic acid 9H-fluoren-9-ylmethyl ester (391624-28-5) → C37H42N6O7 (1252806-22-6)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; for 2h;

DOI:10.1007/s10989-010-9228-6

Reference yield:

N-Fmoc-Val-ψ[CH2-I] → C37H42N6O7 (1252806-22-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 2 h / 20 °C

With sodium azide; copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1007/s10989-010-9228-6

Reference yield:

2-[(S)-(fluoren-9-ylmethoxycarbonyl)amino]-3-methylbutan-1-ol (160885-98-3) → C37H42N6O7 (1252806-22-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1H-imidazole; iodine; triphenylphosphine

2: sodium azide / N,N-dimethyl-formamide / 20 °C

3: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 2 h / 20 °C

With 1H-imidazole; sodium azide; copper(ll) sulfate pentahydrate; iodine; sodium L-ascorbate; triphenylphosphine; In water; N,N-dimethyl-formamide; tert-butyl alcohol; 1: Mitsunobu reaction;

DOI:10.1007/s10989-010-9228-6

upstream raw materials:

C₁₇H₂₀N₂O₅

(1-azidomethyl-2-methyl-propyl)-carbamic acid 9H-fluoren-9-ylmethyl ester

2-[(S)-(fluoren-9-ylmethoxycarbonyl)amino]-3-methylbutan-1-ol

Refernces