Aspirin DL-lysine

Base Information

• Chemical Name: Aspirin DL-lysine
• CAS No.: 62952-06-1
• Molecular Formula: C9H8O4.C6H14N2O2
• Molecular Weight: 326.349
• Hs Code.: 2922509090
• UNII: 2JJ274J145
• DSSTox Substance ID: DTXSID50886518
• Wikidata: Q15041214
• NCI Thesaurus Code: C91032
• ChEMBL ID: CHEMBL1697753
• Mol file: 62952-06-1.mol

Synonyms:acetylsalicylic acid lysinate;Aspegic;aspirin lysinate;aspirin lysine;aspiryl-polylysine;Aspisol;Asprin DL-lysine;Flectadol;L-lysine, 2-(acetyloxy)benzoate (1:1);lysine acetylsalicylate;lysine-acetylsalicylic acid;lysine-aspirin;Solusprin;Solusprin, monosalicylate, (DL-Lys)-isomer;Solusprin, monosalicylate, (L-Lys)-isomer;Venopirin

Chemical Property of Aspirin DL-lysine

Chemical Property:

• Appearance/Colour: Crystalline solid
• Vapor Pressure: 0.000124mmHg at 25°C
• Melting Point: 154-156 °C
• Refractive Index: 1.6280 (estimate)
• Boiling Point: 321.4 °C at 760 mmHg
• Flash Point: 131.2 °C
• PSA: 152.94000
• Density: 1.1829 (rough estimate)
• LogP: 2.23800
• Storage Temp.: -20°C Freezer
• Solubility.: Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 326.14778643
• Heavy Atom Count: 23
• Complexity: 318

Purity/Quality:

99% ^*data from raw suppliers

DL-Lysine acetylsalicylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=CC=CC=C1C(=O)O.C(CCN)CC(C(=O)O)N
• Recent EU Clinical Trials: A monocentric academic trial comparing the diagnostic value of history taking and nasal lysine aspirin provocation test in the diagnosis of AERD in CRSwNP patients
• Uses: Non-steroidal anti-inflammatory drugs (NSAIDs) may inhibit cancer growth. Water soluble, injectable aspirin derivative. Analgesic; antipyretic; anti-inflammatory. Non-steroidal anti-inflammatory drugs (NSAIDs) may inhibit cancer growth. Water soluble, injectable aspirin derivative.Analgesic; antipyretic; anti-inflammatory.

Technology Process of Aspirin DL-lysine

There total 1 articles about Aspirin DL-lysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,6-diaminocaproic acid (70-54-2,923-27-3,6899-06-5,60103-30-2,60132-27-6,56-87-1,3506-25-0) + aspirin (50-78-2,98201-60-6) → lysine Acetylsalicylate (62952-06-1,37933-78-1,77337-52-1)

Guidance literature:

In ethanol; water; for 0.533333h; Time;

upstream raw materials:

2,6-diaminocaproic acid

aspirin

Refernces

• 1、 -. "METHOD FOR PREPARING A SALT OF ACETYLSALICYLIC ACID AND A BASIC AMINO ACID". Paragraph 0079; 0080-0113; 0252. . Retrieved 2017/04/11.