N,N-Dimethyl-1,3-dioxolan-2-amine

Base Information

• Chemical Name: N,N-Dimethyl-1,3-dioxolan-2-amine
• CAS No.: 19449-26-4
• Molecular Formula: C5H11NO2
• Molecular Weight: 117.148
• Hs Code.: 2932999099
• European Community (EC) Number: 243-075-7
• NSC Number: 119918
• UNII: 6X7K32A2CN
• DSSTox Substance ID: DTXSID00173081
• Nikkaji Number: J242.820B
• Wikidata: Q72468916
• Mol file: 19449-26-4.mol

Synonyms:19449-26-4;N,N-Dimethyl-1,3-dioxolan-2-amine;N,N-Dimethylformamide ethylene acetal;2-Dimethylamino-1,3-dioxolane;1,3-Dioxolan-2-amine, N,N-dimethyl-;6X7K32A2CN;EINECS 243-075-7;NSC-119918;N,N-DIMETHYLFORMAMIDEETHYLENEACETAL;dimethylaminodioxolane;NSC119918;UNII-6X7K32A2CN;SCHEMBL131193;MPMQNXVIUFUDEP-UHFFFAOYSA-;DTXSID00173081;[1,3]Dioxolan-2-yl-dimethyl-amine;MFCD00014105;AKOS006230180;NSC 119918;FT-0629541;DIMETHYLFORMAMIDE CYCLIC ETHYLENE ACETAL

Chemical Property of N,N-Dimethyl-1,3-dioxolan-2-amine

Chemical Property:

• Vapor Pressure: 5.85mmHg at 25°C
• Refractive Index: n20/D 1.429
• Boiling Point: 141.453 °C at 760 mmHg
• PKA: 5.00±0.20(Predicted)
• Flash Point: 51.982 °C
• PSA: 21.70000
• Density: 1.042 g/cm³
• LogP: -0.12160
• Sensitive.: Moisture Sensitive
• XLogP3: 0
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 117.078978594
• Heavy Atom Count: 8
• Complexity: 68.8

Purity/Quality:

99% ^*data from raw suppliers

N,N-DIMETHYLFORMAMIDE ETHYLENE ACETAL Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:
• Hazard Codes: R10:
• Statements: 10
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1OCCO1

Technology Process of N,N-Dimethyl-1,3-dioxolan-2-amine

There total 3 articles about N,N-Dimethyl-1,3-dioxolan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethylene glycol (107-21-1) + N,N-dimethylformamide diethyl diacetal (1188-33-6) → N,N-dimethylformamide ethylene acetal (19449-26-4)

Guidance literature:

at 20 ℃; for 2h;

DOI:10.1007/BF00633170

Reference yield:

1,4,6,9-tetraoxa-5λ5-phosphaspiro[4,4]nonane (3646-10-4,54515-09-2,673460-28-1) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → methoxy-2 dioxaphospholane-1,3,2 (3741-36-4) + N,N-dimethylformamide ethylene acetal (19449-26-4)

Guidance literature:

at 100 - 120 ℃;

Reference yield:

2-(2'-hydroxyethoxy)-1,3,2-dioxaphospholane (1073-75-2) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → methoxy-2 dioxaphospholane-1,3,2 (3741-36-4) + N,N-dimethylformamide ethylene acetal (19449-26-4)

Guidance literature:

at 110 - 130 ℃; Inert atmosphere;

DOI:10.1002/hc.20552

upstream raw materials:

ethylene glycol

N,N-dimethylformamide diethyl diacetal

1,4,6,9-tetraoxa-5λ₅-phosphaspiro[4,4]nonane

N,N-dimethyl-formamide dimethyl acetal

Downstream raw materials:

ethylene glycol

N,N-dimethyl-formamide

[1,3]-dioxolan-2-one

ethyl N,N-dimethylcarbamate

Refernces

• 1、 Prishchenko, Andrey A.,Livantsov, Mikhail V.,Novikova, Olga P.,Livantsova, Ludmila I.,Petrosyan, Valery S.. "Synthesis of the new types of N-substituted aminomethylenebisorganophosphorus acids and their derivatives". experimental part. p. 319 - 324. Retrieved 2010/08/05.