(S)-2-Amino-5-guanidinopentanoic acid 2-oxopentanedioic acid (2:1)

Base Information

• Chemical Name: (S)-2-Amino-5-guanidinopentanoic acid 2-oxopentanedioic acid (2:1)
• CAS No.: 5256-76-8
• Molecular Formula: C₅H₆O₅*C₆H₁₄N₄O₂
• Molecular Weight: 320.302
• European Community (EC) Number: 226-059-4
• UNII: I9LFI257OB
• Wikidata: Q27280611
• Mol file: 5256-76-8.mol

Synonyms:diarginine-alpha-ketoglutarate;eucol

Chemical Property of (S)-2-Amino-5-guanidinopentanoic acid 2-oxopentanedioic acid (2:1)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 914.9oC at 760 mmHg
• Flash Point: 507.1oC
• PSA: 342.11000
• LogP: 0.61050
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 14
• Exact Mass: 494.24487469
• Heavy Atom Count: 34
• Complexity: 347

Purity/Quality:

99% ^*data from raw suppliers

Di-Arginine oxoglurate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(C(=O)O)N)CN=C(N)N.C(CC(C(=O)O)N)CN=C(N)N.C(CC(=O)O)C(=O)C(=O)O
• Isomeric SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N.C(C[C@@H](C(=O)O)N)CN=C(N)N.C(CC(=O)O)C(=O)C(=O)O

Technology Process of (S)-2-Amino-5-guanidinopentanoic acid 2-oxopentanedioic acid (2:1)

There total 2 articles about (S)-2-Amino-5-guanidinopentanoic acid 2-oxopentanedioic acid (2:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-arginine (74-79-3,25212-18-4) + dimethyl 2,2-dichloro-1,5-pentanedioate (42964-50-1) → L-arginine α-ketoglutarate (16856-18-1,5256-76-8)

Guidance literature:

dimethyl 2,2-dichloro-1,5-pentanedioate; Alkaline conditions;

pH=> 4.5; Acidic aqueous solution;

L-arginine; In water; pH=3 - 4;

Reference yield:

L-arginine (74-79-3,25212-18-4) + dimethyl 2,2-dichloro-1,5-pentanedioate (42964-50-1) → α-ketoglutaric acid di-L-arginine salt (16856-18-1,5256-76-8)

Guidance literature:

dimethyl 2,2-dichloro-1,5-pentanedioate; Alkaline conditions;

pH=> 4.5; Acidic aqueous solution;

L-arginine; In water; pH=6.5 - 7;

upstream raw materials:

L-arginine

dimethyl 2,2-dichloro-1,5-pentanedioate

Refernces

• 1、 -. "Process for preparation of L-Arginine alpha-ketoglutarate 1:1 and 2:1". Page/Page column 3. . Retrieved 2012/04/23.