Glyphosine

Base Information Edit

Chemical Name:Glyphosine
CAS No.:2439-99-8
Molecular Formula:C4H11NO8P2
Molecular Weight:263.081
Hs Code.:HOSINE PRODUCT IDENTIFICATION
Mol file:2439-99-8.mol

Synonyms:C 9552;CP41845;Glycine-N,N-bis(methylenephosphonic acid);Glycinedimethanephosphonicacid;Glyphosine;MON 845;MON-O45;N,N-Bis(phosphonomethyl)aminoacetic;N,N-Bis(phosphonomethyl)aminoacetic acid;N,N-Bis(phosphonomethyl)glycine;N,N-Di(phosphonomethyl)glycine;NSC 18468;Nitrilomonoacetic aciddimethylenephosphonic acid;Nitrilomonomethylcarbonyldimethylphosphonic acid;Polaris;Polaris (ripening agent);

Suppliers and Price of Glyphosine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Glyphosine
5g
$ 220.00

TCI Chemical
Glycine-N,N-bis(methylenephosphonic Acid)
5G
$ 59.00

Sigma-Aldrich
N,N-Bis(phosphonomethyl)glycine ≥98.0% (T)
50g
$ 455.00

Sigma-Aldrich
N,N-Bis(phosphonomethyl)glycine ≥98.0% (T)
10g
$ 136.00

Sigma-Aldrich
Glyphosine - CAS 2439-99-8 - Calbiochem Aplantgrowthregulatorthatalsoenhancesanti-B:9-23TCR-dependentTcellact
5 g
$ 135.00

Sigma-Aldrich
Glyphosine - CAS 2439-99-8 - Calbiochem
5gm
$ 126.00

Crysdot
2-(Bis(phosphonomethyl)amino)aceticacid 97%
5g
$ 40.00

Crysdot
2-(Bis(phosphonomethyl)amino)aceticacid 97%
10g
$ 70.00

Crysdot
2-(Bis(phosphonomethyl)amino)aceticacid 97%
25g
$ 140.00

Chem-Impex
N,N-Bis(phosphonomethyl)glycine,98%(Assaybytitration) 98%(Assaybytitration)
1G
$ 16.80

Total 64 raw suppliers

Chemical Property of Glyphosine Edit

Chemical Property:

Appearance/Colour:white to light yellow crystalline powder
Vapor Pressure:1.35E-19mmHg at 25°C
Melting Point:263 °C
Refractive Index:1.594
Boiling Point:668.4 °C at 760 mmHg
PKA:pK1 1.42; pK2 2.10; pK3 5.02; pK4 6.40; pK5 11.19(at 25℃)
Flash Point:358 °C
PSA：175.22000
Density:1.952 g/cm³
LogP:-1.35660
Storage Temp.:+2C to +8C
Water Solubility.:248g/L(20 oC)
XLogP3:-6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:262.99599030
Heavy Atom Count:15
Complexity:314

Purity/Quality:

98%,99%, ^*data from raw suppliers

Glyphosine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-2

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(C(=O)O)[NH+](CP(=O)(O)O)CP(=O)(O)[O-]
Uses Chemical ripener; plant growth regulator. Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89 Anti-diabetic; delay onset of diabetes in non-obese NOD miceGlyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.

Technology Process of Glyphosine

There total 13 articles about Glyphosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 178883-78-8
O-trimethylsilyl N,N-bis[bis(trimethylsiloxy)phosphorylmethyl]glycine

: 2439-99-8
<<(carboxymethyl)imino>dimethylene>bisphosphonic acid

Guidance literature:: In methanol; diethyl ether; at 10 ℃; Inert atmosphere;
DOI:10.1002/hc.20616

Reference yield: 83.0%

: 123959-98-8
N,N-bis<(dimethoxyphosphinyl)methyl>glycine

: 2439-99-8
<<(carboxymethyl)imino>dimethylene>bisphosphonic acid

Guidance literature:: N,N-bis<(dimethoxyphosphinyl)methyl>glycine; With trimethylsilyl bromide; In acetonitrile; at 0 - 20 ℃; for 15.5h;

With methanol; for 0.5h;

With water; at 20 ℃; for 1h;