Profenofos

Base Information

• Chemical Name: Profenofos
• CAS No.: 41198-08-7
• Deprecated CAS: 61230-42-0,61287-51-2,61287-51-2,92760-41-3
• Molecular Formula: C11H15BrClO3PS
• Molecular Weight: 373.635
• Hs Code.: 29309090
• European Community (EC) Number: 255-255-2
• UN Number: 3018
• UNII: 7J04O7BS4W
• DSSTox Substance ID: DTXSID3032464
• Nikkaji Number: J15.829A
• Wikipedia: Profenofos
• Wikidata: Q2111894
• Metabolomics Workbench ID: 56030
• ChEMBL ID: CHEMBL2138242
• Mol file: 41198-08-7.mol

Synonyms:Curacron;profenofos;Selecron

Chemical Property of Profenofos

Chemical Property:

• Appearance/Colour: pale yellow liquid with garlic-like odor
• Vapor Pressure: 2.66E-06mmHg at 25°C
• Melting Point: <25 °C
• Refractive Index: 1.552
• Boiling Point: 401.8 °C at 760 mmHg
• Flash Point: 196.8 °C
• PSA: 70.64000
• Density: 1.482 g/cm³
• LogP: 5.76910
• Storage Temp.: APPROX 4°C
• Water Solubility.: 28 mg l-1 (25 °C)
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 371.93514
• Heavy Atom Count: 18
• Complexity: 296
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

Profenofos ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N,T
• Statements: 20/21/22-50/53-24-20/22-43
• Safety Statements: 36/37-60-61-45-9-7

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl
• Description: Profenofos is a pale yellow liquid, bp 100 ?C/1.80 Pa, vp 0.124 mPa (25 ?C). Solubility in water is 28 mg/L (25 ?C). It is miscible with most organic solvents. Log Kow = 4.44. It is relatively stable in neutral and mild acid media but hydrolyzed in alkaline media; DT50 values (20 ?C) at pH 5, 7, and 9 are 93 d, 14.6 d, and 5.7 h, respectively.
• Uses: A broad-spectrum organophosphorous pesticide that is used widely in cotton fields for insect control. Insecticide; acaricide. Profenofos is used to control insects (particularly caterpillars and Lepidoptera eggs) and mites on cotton, maize, sugar beet, soyabean, potatoes, vegetables, tobacco and a number of other crops

Technology Process of Profenofos

There total 1 articles about Profenofos which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Profenofos (41198-08-7)

Guidance literature:

2-Chlor-4-bromphenol, O-Ethyl-S-n-propylchlorthiophosphat;

Reference yield: 43.9%

Profenofos (41198-08-7) → ethyl phosphodichloridite (1498-51-7) + thiophosphorochloridic acid O-(4-bromo-2-chloro-phenyl) ester S-propyl ester

Guidance literature:

With trichlorophosphate; at 100 ℃; for 4h;

DOI:10.1080/10426509808029665

Reference yield:

Profenofos (41198-08-7) + 3-chloro-benzenecarboperoxoic acid (937-14-4) → propanesulfonic acid (5284-66-2) + Phosphoric acid 4-bromo-2-chloro-phenyl ester ethyl ester (80705-86-8) + C11H15BrClO6PS (80705-85-7) + C15H12BrCl2O5P (80705-87-9)

Guidance literature:

In acetone; at 25 ℃; for 1h; Further byproducts given;

DOI:10.1016/S0040-4039(00)86768-4

Downstream raw materials:

propanesulfonic acid

Phosphoric acid 4-bromo-2-chloro-phenyl ester ethyl ester

C₁₁H₁₅BrClO₆PS

C₁₅H₁₂BrCl₂O₅P

Refernces

• 1、 -. "Insecticidal composition for agricultural and horticultural use". . . Retrieved 2008/06/13.