2-(Trifluoromethyl)aniline

Base Information Edit

Chemical Name:2-(Trifluoromethyl)aniline
CAS No.:88-17-5
Molecular Formula:C7H6F3N
Molecular Weight:161.127
Hs Code.:29214300
European Community (EC) Number:201-806-7
NSC Number:10336
UN Number:2942
UNII:I1R59842CE
DSSTox Substance ID:DTXSID7058961
Nikkaji Number:J59.713I
Wikidata:Q27280261
ChEMBL ID:CHEMBL249549
Mol file:88-17-5.mol

Synonyms:2-(TRIFLUOROMETHYL)ANILINE;2-Aminobenzotrifluoride;88-17-5;o-Aminobenzotrifluoride;2-Trifluoromethylaniline;o-(Trifluoromethyl)aniline;o-Trifluoromethylaniline;Benzenamine, 2-(trifluoromethyl)-;2-(Trifluoromethyl)benzenamine;alpha,alpha,alpha-Trifluoro-o-toluidine;2-Trifluoromethyl-phenylamine;2-aminotrifluorotoluene;MFCD00007718;NSC 10336;CCRIS 2811;EINECS 201-806-7;UN2942;2-trifluoromethylphenylamine;2-(trifluoromethyl) aniline;2-aminotrifluoromethylbenzene;o-(Trifluoromethyl)phenylamine;AI3-26182;I1R59842CE;1-amino-2-(trifluoromethyl)benzene;o-Toluidine, .alpha.,.alpha.,.alpha.-trifluoro-;NSC-10336;o-Toluidine, alpha,alpha,alpha-trifluoro-;.alpha.,.alpha.,.alpha.-Trifluoro-o-toluidine;EC 201-806-7;a,a,a-Trifluoro-O-toluidine;2-trifluoromethylanilin;2-Trifluromethylaniline;o-Amino Benzotrifluoride;o-trifluoromethyl aniline;2-trifluoromethyl aniline;2-trifluoromethyl-aniline;ortho trifluoromethylaniline;2-(trifluoromethyl)-aniline;2-trifluoromethyl phenylamine;SCHEMBL70554;BIDD:GT0808;UNII-I1R59842CE;CHEMBL249549;2-(trifluoromethyl)-Benzenamine;DTXSID7058961;[2-(trifluoromethyl)phenyl]amine;Bencenamina, 2-(trifluorometil)-;2-(Trifluoromethyl)aniline, 99%;NSC10336;alpha-alpha-alpha-trifluor-o-toluidin;NA2942;PC1020;STL163342;AKOS000119176;.alpha.,.alpha.-Trifluoro-o-toluidine;AM87357;AT20036;CS-W004108;PS-8764;UN 2942;AC-10748;LS-188096;A0433;A7166;FT-0656621;2-Trifluoromethylaniline [UN2942] [Poison];EN300-19102;2-Aminotrifluorotoluene 2-Trifluoromethylaniline;2-Trifluoromethylaniline [UN2942] [Poison];W-100414;Q27280261;F2190-0434;Z104472784;2-AMINO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUOROTOLUENE

Suppliers and Price of 2-(Trifluoromethyl)aniline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Aminobenzotrifluoride
2.5g
$ 120.00

TRC
2-Aminobenzotrifluoride
10g
$ 140.00

TRC
2-Aminobenzotrifluoride
25g
$ 165.00

TCI Chemical
2-Aminobenzotrifluoride >98.0%(GC)(T)
500mL
$ 164.00

TCI Chemical
2-Aminobenzotrifluoride >98.0%(GC)(T)
25mL
$ 29.00

SynQuest Laboratories
2-Aminobenzotrifluoride 99%
1 kg
$ 104.00

SynQuest Laboratories
2-Aminobenzotrifluoride 99%
500 g
$ 56.00

Sigma-Aldrich
2-(Trifluoromethyl)aniline 99%
100g
$ 43.10

Sigma-Aldrich
2-(Trifluoromethyl)aniline 99%
5g
$ 18.70

Frontier Specialty Chemicals
2-Aminobenzotrifluoride 99%
100g
$ 44.00

Total 137 raw suppliers

Chemical Property of 2-(Trifluoromethyl)aniline Edit

Chemical Property:

Appearance/Colour:clear colorless to light amber liquid
Vapor Pressure:2.1-12.1hPa at 20-50℃
Melting Point:34 °C(lit.)
Refractive Index:n20/D 1.481(lit.)
Boiling Point:174.8 °C at 760 mmHg
PKA:1.10±0.10(Predicted)
Flash Point:55 °C
PSA：26.02000
Density:1.286 g/cm³
LogP:2.86880
Storage Temp.:Store below +30°C.
Solubility.:4g/l
Water Solubility.:4 g/L (20 ºC)
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:161.04523368
Heavy Atom Count:11
Complexity:132
Transport DOT Label:Poison

Purity/Quality:

≥99% ^*data from raw suppliers

2-Aminobenzotrifluoride ^*data from reagent suppliers

Safty Information:

Pictogram(s): T, Xi, Xn, F
Hazard Codes:T,Xi,Xn,F
Statements: 10-23/24/25-33-36/37/38-22-20/21/22
Safety Statements: 36/37/39-45-37/39-26-16-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(F)(F)F)N

Technology Process of 2-(Trifluoromethyl)aniline

There total 73 articles about 2-(Trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 344-62-7
N-[2-(trifluoromethyl)phenyl]acetamide

: 88-17-5
2-(trifluoromethyl)benzenamine

Guidance literature:: With thionyl chloride; In methanol; at 75 ℃; for 3h;
DOI:10.1039/c9cc01014a

Reference yield: 89.0%

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 62-53-3
aniline

: 88-17-5
2-(trifluoromethyl)benzenamine

Guidance literature:: With 1-acetoxy-1,2-benziodoxol-3-one; potassium acetate; In acetonitrile; at 80 ℃; for 13h; Reagent/catalyst; Solvent; Temperature; Time;