2,4,6-Trichlorophenylhydrazine

Base Information

• Chemical Name: 2,4,6-Trichlorophenylhydrazine
• CAS No.: 5329-12-4
• Molecular Formula: C6H5Cl3N2
• Molecular Weight: 211.478
• Hs Code.: 29280000
• European Community (EC) Number: 226-217-2
• NSC Number: 1869
• UNII: 3ARF2RVG9W
• DSSTox Substance ID: DTXSID5063780
• Nikkaji Number: J29.951K
• Wikidata: Q72510359
• Mol file: 5329-12-4.mol

Synonyms:2,4,6-trichlorophenylhydrazine;2,4,6-trichlorophenylhydrazine monohydrochloride;2,4,6-trichlorophenylhydrazine sulfate (1:1) salt

Chemical Property of 2,4,6-Trichlorophenylhydrazine

Chemical Property:

• Vapor Pressure: 0.00574mmHg at 25°C
• Melting Point: 140-142 °C(lit.)
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 273.4 °C at 760 mmHg
• PKA: 3.80±0.33(Predicted)
• Flash Point: 119.2 °C
• PSA: 38.05000
• Density: 1.603 g/cm³
• LogP: 3.70570
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility.: benzene: 0.1 g/mL, clear
• Water Solubility.: Soluble in acetone. Insoluble in water.
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 209.951831
• Heavy Atom Count: 11
• Complexity: 121

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4,6-Trichlorophenylhydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)NN)Cl)Cl
• Uses: 2,4,6-Trichlorophenylhydrazine is used as a pharmaceutical intermediate.

Technology Process of 2,4,6-Trichlorophenylhydrazine

There total 17 articles about 2,4,6-Trichlorophenylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

→ 2,3,4-trichlorophenylhydrazine (80025-74-7) + (2,4,6-trichlorophenyl)hydrazine (5329-12-4)

Guidance literature:

Reference yield: 50.0%

2,4,6-trichloronitrobenzene (18708-70-8) → (2,4,6-trichlorophenyl)hydrazine (5329-12-4)

Guidance literature:

With hydrazine hydrate; In benzene; for 5h; Heating;

Reference yield:

N-phthaliminoaniline + ethanol (64-17-5) → (2,4,6-trichlorophenyl)hydrazine (5329-12-4)

Guidance literature:

With hydrogenchloride; sodium hydroxide; sulfuryl dichloride; In tetrachloromethane; water;

upstream raw materials:

N-chloro-N'-(2,4,6-trichloro-phenyl)-urea

sodium ethanolate

N-(2,4,6-trichloro)phenylbenzhydrazidoyl chloride

methanol

Downstream raw materials:

2-methyl-4,6-diphenyl-1-(2,4,6-trichloro-anilino)-pyridinium; iodide

3-(1H-imidazol-1-yl)heptan-4-one 2,4,6-trichlorophenylhydrazone

N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-N'-(2,4,6-trichlorophenyl)hydrazine

Refernces

• 1、 -. "Process for producing chlorophenylhydrazine compounds". . . Retrieved 2008/06/13.
• 2、 Kirschke, Klaus,Moeller, Angela,Schmitz, Ernst. "New Azoolefines and their Acidic Cleavage to Aryldiimines". . p. 893 - 898. Retrieved 2007/10/02.