Pyrimidine-2,4,5,6-tetraamine dihydrochloride

Base Information

• Chemical Name: Pyrimidine-2,4,5,6-tetraamine dihydrochloride
• CAS No.: 39944-62-2
• Molecular Formula: C₄H₈N₆*2ClH
• Molecular Weight: 213.07
• Hs Code.: 2933599090
• European Community (EC) Number: 619-990-6,610-924-1
• DSSTox Substance ID: DTXSID90494393
• Mol file: 39944-62-2.mol

Synonyms:39944-62-2;Pyrimidine-2,4,5,6-tetraamine dihydrochloride;2,4,5,6-Tetraaminopyrimidine dihydrochloride;52980-67-3;Pyrimidinetetramine, hydrochloride;pyrimidine-2,4,5,6-tetramine;dihydrochloride;PYRIMIDINE-2,4,5,6-TETRAMINE DIHYDROCHLORIDE;EC 619-990-6;Pyrimidine, 2,4,5,6-tetraamine, dihydrochloride;SCHEMBL63511;DTXSID90494393;BKYYVSKCYPCEAU-UHFFFAOYSA-N;AKOS015892520;AM81331;SB58465;AS-61660;CS-0320147;FT-0658791;Pyrimidine-2,4,5,6-tetraaminedihydrochloride;D87791;Pyrimidine-2,4,5,6-tetramine--hydrogen chloride (1/2)

Chemical Property of Pyrimidine-2,4,5,6-tetraamine dihydrochloride

Chemical Property:

• Appearance/Colour: light yellow to white crystal
• Vapor Pressure: 8.68E-12mmHg at 25°C
• Boiling Point: 534.9ºC at 760 mmHg
• Flash Point: 277.3°C
• PSA: 129.86000
• LogP: 2.73420
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 212.0343997
• Heavy Atom Count: 12
• Complexity: 104

Purity/Quality:

99.9% ^*data from raw suppliers

Pyrimidine-2,4,5,6-tetraamineDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(N=C(N=C1N)N)N)N.Cl.Cl

Technology Process of Pyrimidine-2,4,5,6-tetraamine dihydrochloride

There total 1 articles about Pyrimidine-2,4,5,6-tetraamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,5,6-tetraaminopyrimidine sulfate (5392-28-9,49647-58-7) → 2,4,5,6-tetraamino-pyrimidine dihydrochloride (39944-62-2,51093-30-2,52980-67-3,65540-06-9)

Guidance literature:

With barium(II) chloride; In water; at 85 - 90 ℃; for 0.25h;

Reference yield: 93.0%

oxo-phenyl-acetaldehyde oxime (532-54-7) + 2,4,5,6-tetraamino-pyrimidine dihydrochloride (39944-62-2,51093-30-2,52980-67-3,65540-06-9) → 2,4-Diamino-6-(phenyl)pteridine (1026-36-4)

Guidance literature:

In methanol; for 2h; Heating;

DOI:10.1016/S0040-4039(97)01619-5

Reference yield: 91.0%

p-methoxy-isonitrosoacetophenone (1823-76-3) + 2,4,5,6-tetraamino-pyrimidine dihydrochloride (39944-62-2,51093-30-2,52980-67-3,65540-06-9) → 2,4-diamino-6-(p-methoxyphenyl)pteridine (192587-18-1)

Guidance literature:

In methanol; for 2h; Heating;

DOI:10.1021/jm981129a

upstream raw materials:

2,4,5,6-tetraaminopyrimidine sulfate

Downstream raw materials:

2,4,7-Triamino-6-(2-furyl)-pteridin

2,4-diamino-6-chloromethylpteridine

2,4-Diamino-6-(phenyl)pteridine

2,4-diamino-6-methylpteridine

Refernces

• 1、 -. "Compositions and methods employing aminopterin". Page/Page column 16. . Retrieved 2008/06/13.