Technology Process of 5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-1,3,4-oxadiazole-2-thiol
There total 5 articles about 5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-1,3,4-oxadiazole-2-thiol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbon disulfide; 4-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid hydrazide;
With
potassium hydroxide;
In
ethanol; water;
for 10h;
Reflux;
With
hydrogenchloride;
In
water;
DOI:10.1007/s00044-012-0112-0
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrazine hydrate / ethanol / 3 h / Reflux
2: potassium hydroxide / ethanol; water / 10 h / Reflux
With
hydrazine hydrate; potassium hydroxide;
In
ethanol; water;
DOI:10.1007/s00044-012-0112-0
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetic acid / 1 h / Reflux
2: hydrazine hydrate / ethanol / 3 h / Reflux
3: potassium hydroxide / ethanol; water / 10 h / Reflux
With
hydrazine hydrate; acetic acid; potassium hydroxide;
In
ethanol; water;
1: |Paal-Knorr Pyrrole Synthesis;
DOI:10.1007/s00044-012-0112-0
