N-Benzylglycine hydrochloride

Base Information

• Chemical Name: N-Benzylglycine hydrochloride
• CAS No.: 7689-50-1
• Molecular Formula: C9H11NO2.HCl
• Molecular Weight: 201.653
• Hs Code.: 29224999
• European Community (EC) Number: 629-151-6
• NSC Number: 25487
• DSSTox Substance ID: DTXSID70373450
• Mol file: 7689-50-1.mol

Synonyms:7689-50-1;N-Benzylglycine hydrochloride;Bzl-Gly-OH.HCl;Benzylaminoacetic acid hydrochloride;2-(benzylamino)acetic Acid Hydrochloride;N-Benzylglycine, HCl;MFCD00156934;2-(benzylamino)acetic acid;hydrochloride;Glycine, N-(phenylmethyl)-, hydrochloride;Bzl-Gly-OH inverted exclamation mark currencyHCl;Bz-Gly-OH.HCl;N-benzylglycine HCl;benzylglycine hydrochloride;Bzl-Gly-OH . HCl;BenzylaMinoacetic acid HCl;SCHEMBL1252387;2-(Benzylamino)acetic acid HCl;AMY4105;DTXSID70373450;BUZJPENZWLUHJD-UHFFFAOYSA-N;HY-Y0735;NSC25487;benzyl(carboxymethyl)azanium;chloride;N-Benzylglycine hydrochloride, 98%;NSC-25487;AKOS015848422;DS-1118;AC-19213;SY015802;A9740;B3075;CS-0015734;FT-0636565;EN300-56216;Q-103182;F0001-1969;2-(benzylamino)acetic acid hydrochloride;N-Benzylglycine Hydrochloride

Chemical Property of N-Benzylglycine hydrochloride

Chemical Property:

• Appearance/Colour: crystalline
• Vapor Pressure: 0.000285mmHg at 25°C
• Melting Point: 232 °C (dec.)(lit.)
• Boiling Point: 308.9 °C at 760 mmHg
• Flash Point: 140.6 °C
• PSA: 49.33000
• LogP: 2.05370
• Storage Temp.: Store at RT.
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 201.0556563
• Heavy Atom Count: 13
• Complexity: 142

Purity/Quality:

98%min ^*data from raw suppliers

N-Benzyl glycine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNCC(=O)O.Cl

Technology Process of N-Benzylglycine hydrochloride

There total 6 articles about N-Benzylglycine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) + glycine (56-40-6,18875-39-3,25718-94-9) → N-benzyl glycine hydrochloride (7689-50-1)

Guidance literature:

benzaldehyde; glycine; With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃;

With hydrogenchloride; In ethyl acetate; 1,2-dichloro-ethane;

DOI:10.1016/j.ejmech.2021.113954

Reference yield:

ethyl 2-(benzylamino)acetate (6436-90-4) + ethyl bromoacetate (105-36-2) + benzylamine (100-46-9) → N-benzyl glycine hydrochloride (7689-50-1)

Guidance literature:

In hydrogenchloride; acetone;

Reference yield:

N-benzyl-N-formyl-glycine (86731-89-7) → N-benzyl glycine hydrochloride (7689-50-1)

Guidance literature:

With hydrogenchloride; Heating;

DOI:10.1055/s-2007-982531

upstream raw materials:

2-(N-benzyl-4-methylphenylsulfonamido)acetic acid

acetic acid

N-benzyl-N-formyl-glycine

benzylamine

Downstream raw materials:

N-benzyl-N-(tert-butoxycarbonyl)glycine

N-benzyl-N-benzyloxycarbonyl-glycine

Refernces

• 1、 Roche, Stéphane P.,Richaud, Alexis D.. "Structure-property relationship study of n-(hydroxy)peptides for the design of self-assembled parallel β-sheets". . p. 12329 - 12342. Retrieved 2020/11/10.
• 2、 -. "Polypeptide having an amino acid replaced with N-benzylglycine". . . Retrieved 2008/06/13.