Lufenuron

Base Information

• Chemical Name: Lufenuron
• CAS No.: 103055-07-8
• Molecular Formula: C₁₇H₈Cl₂F₈N₂O₃
• Molecular Weight: 511.155
• Hs Code.: 29242990
• European Community (EC) Number: 410-690-9,600-387-1
• NSC Number: 759097
• UNII: 4629851K7Q,1R754M4918,9CR45YMS74
• DSSTox Substance ID: DTXSID5034357
• Nikkaji Number: J481.190I
• Wikipedia: Lufenuron
• Wikidata: Q412933
• NCI Thesaurus Code: C76874
• RXCUI: 83586
• Metabolomics Workbench ID: 56276
• ChEMBL ID: CHEMBL1364906
• Mol file: 103055-07-8.mol

Synonyms:CGA 184699;CGA-184699;fluphenacur;fluphenacur, monosodium salt;lufenuron;N-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylaminocarbonyl)-2,6-difluorobenzamide

Chemical Property of Lufenuron

Chemical Property:

• Appearance/Colour: COA
• Vapor Pressure: <0.4 x10 -3 Pa (25 °C)
• Melting Point: 174.1°
• Refractive Index: 1.522
• PKA: 8.49±0.46(Predicted)
• Flash Point: 170 °C
• PSA: 67.43000
• Density: 1.631 g/cm³
• LogP: 6.56940
• Storage Temp.: 0-6°C
• Solubility.: 100mg/L in organic solvents at 20 ℃
• Water Solubility.: <0.06 mg l-1(25 °C)
• XLogP3: 6.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 5
• Exact Mass: 509.9784228
• Heavy Atom Count: 32
• Complexity: 677

Purity/Quality:

97%, ^*data from raw suppliers

Lufenuron ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,N
• Hazard Codes: Xi;N,N,Xi
• Statements: 43-50/53
• Safety Statements: 2-24-37-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
• Recent ClinicalTrials: Safety Evaluation of a Lifestyle Modification Program In.Form 1.1
• Description: Lufenuron is an insect development inhibitor of the benzoylphenyl urea class. It demonstrates activity against fleas that have fed on treated cats and dogs and become exposed to lufenuron in the host’s blood. Lufenuron also has activity by virtue of its presence in adult flea feces, leading to its ingestion by flea larvae. Both activities result in the production of eggs that are unable to hatch, causing significant reductions in flea larvae populations. The lipophilicity of lufenuron leads to its deposition in adipose tissues of animals from where it is slowly released into the bloodstream. This permits effective blood concentrations to be maintained throughout the recommended oral dosing interval of 1 month.
• Uses: Lufenuron is used for the control of Lepidoptera and Coleoptera larvae on cotton, maize and vegetables, and of citrus whitefly and rust mites on citrus fruit. It is also used to control fleas on pets and cockroaches in houses.

Technology Process of Lufenuron

There total 1 articles about Lufenuron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ lufenuron (103055-07-8)

Guidance literature:

Refernces

• 1、 -. "Insecticidal combination to control mammal fleas, in particular fleas on cats and dogs". . . Retrieved 2008/06/13.