allyl 2-(N-allylamino)benzoate

Base Information

• Chemical Name: allyl 2-(N-allylamino)benzoate
• CAS No.: 1023287-68-4
• Molecular Formula: C₁₃H₁₅NO₂
• Molecular Weight: 217.268
• Mol file: 1023287-68-4.mol

Synonyms:allyl 2-(N-allylamino)benzoate

Chemical Property of allyl 2-(N-allylamino)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of allyl 2-(N-allylamino)benzoate

There total 2 articles about allyl 2-(N-allylamino)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) + allyl bromide (106-95-6) → allyl 2-(N-allylamino)benzoate (1023287-68-4) + anthranilic acid allyl ester (7493-63-2)

Guidance literature:

anthranilic acid; With potassium hydroxide; at 20 ℃;

allyl bromide; In N,N-dimethyl-formamide; at 20 ℃; Further stages.;

DOI:10.1002/jhet.5570450222

Reference yield: 7.0%

allyl bromide (106-95-6) + indirubin (479-41-4) → allyl 2-(N-allylamino)benzoate (1023287-68-4) + 1,9a'-diallyl-8'H-spiro[indoline-3,9'-pyrido[1,2-a]indole]-2,10'(9a'H)-dione

Guidance literature:

indirubin; With caesium carbonate; In N,N-dimethyl-formamide; at 70 ℃; Inert atmosphere; Molecular sieve;

allyl bromide; In N,N-dimethyl-formamide; at 70 - 110 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2015.08.012

upstream raw materials:

anthranilic acid

allyl bromide

indirubin

Refernces

• 1、 Sele, Alexander M.,Bremner, John B.,Willis, Anthony C.,Haritakun, Rachada,Griffith, Renate,Keller, Paul A.. "A cascade synthetic route to new bioactive spiroindolinepyrido[1,2-a]indolediones from indirubin". . p. 8357 - 8367. Retrieved 2015/10/05.