para-trifluoromethylbenzenesulphonic acid

Base Information

• Chemical Name: para-trifluoromethylbenzenesulphonic acid
• CAS No.: 109787-11-3
• Molecular Formula: C₇H₅F₃O₃S
• Molecular Weight: 226.176
• Mol file: 109787-11-3.mol

Synonyms:para-trifluoromethylbenzenesulphonic acid

Chemical Property of para-trifluoromethylbenzenesulphonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of para-trifluoromethylbenzenesulphonic acid

There total 7 articles about para-trifluoromethylbenzenesulphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-trifluorophenylsulfonyl chloride (2991-42-6) → para-trifluoromethylbenzenesulphonic acid (109787-11-3)

Guidance literature:

With water; In 1,4-dioxane; for 6h; Reflux;

DOI:10.1021/acs.orglett.1c00994

Reference yield:

4-(trifluoromethyl)benzenesulfonamide (830-43-3) → para-trifluoromethylbenzenesulphonic acid (109787-11-3)

Guidance literature:

With pyrylium tetrafluoroborate; In tert-butyl alcohol; at 60 ℃; for 3h;

DOI:10.1002/anie.201910895

Reference yield:

3-hydroxybutyl 4-(trifluoromethyl)benzenesulfonate (1242141-25-8) → para-trifluoromethylbenzenesulphonic acid (109787-11-3)

Guidance literature:

With perfluorobutanesulfonic acid; In 3-ethylphenol; benzene-d6; at 100 ℃; Concentration; Reagent/catalyst; Kinetics;

DOI:10.1021/cm101867g

upstream raw materials:

4-trifluorophenylsulfonyl chloride

3-hydroxy-3-methylbutyl 4-(trifluoromethyl)benzenesulfonate

3-hydroxybutyl 4-(trifluoromethyl)benzenesulfonate

4-(trifluoromethyl)benzenesulfonamide

Downstream raw materials:

4-trifluoromethylbenzenethiol

(1R,2R)-N,N'-bis(4-trifluoromethylbenzenesulfonyl)-cyclohexane-1,2-diamine

(E)-4-trifluoromethyl-1-(phenylethenylsulfonyl)benzene

N-hydroxy-2-((4-(trifluoromethyl)phenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide

Refernces

• 1、 Bourbon, Paul,Appert, Emeline,Martin-Mingot, Agnès,Michelet, Bastien,Thibaudeau, Sébastien. "Complementary Site-Selective Sulfonylation of Aromatic Amines by Superacid Activation". supporting information. p. 4115 - 4120. Retrieved 2021/06/21.
• 2、 -. "Novel anthracene derivative and radiation-sensitive resin composition". . . Retrieved 2008/06/13.