6-{2-Chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride

Base Information

• Chemical Name: 6-{2-Chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride
• CAS No.: 25507-04-4
• Molecular Formula: C18H33ClN2O5S^.HCl
• Molecular Weight: 699.864
• Hs Code.: 2941906000
• European Community (EC) Number: 607-740-9
• NCI Thesaurus Code: C61683
• RXCUI: 91075
• Mol file: 25507-04-4.mol

Synonyms:7-chloro-7-deoxylincomycin palmitate;7-chlorolincomycin palmitate;Cleocin palmitate;clindamycin palmitate;clindamycin palmitate hydrochloride

Chemical Property of 6-{2-Chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride

Chemical Property:

• Vapor Pressure: 3.44E-27mmHg at 25°C
• Melting Point: 141-143 °C
• Boiling Point: 767.4 °C at 760 mmHg
• Flash Point: 417.9 °C
• PSA: 133.63000
• LogP: 7.55250
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 23
• Exact Mass: 698.3862143
• Heavy Atom Count: 45
• Complexity: 810

Purity/Quality:

98%min ^*data from raw suppliers

Clindamycin Palmitate Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OC1C(C(C(OC1SC)C(C(C)Cl)NC(=O)C2CC(CN2C)CCC)O)O.Cl
• Description: Clindamycin palmitate is a water-soluble prodrug form of the antibiotic clindamycin . It undergoes rapid hydrolysis in vivo to release active clindamycin. Formulations containing clindamycin palmitate have been used in the treatment of various bacterial infections.
• Uses: Clindamycin Palmitate is a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial. antibacterial (tuberculostatic)

Technology Process of 6-{2-Chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride

There total 1 articles about 6-{2-Chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Clindamycin-2-palmitat-hydrochlorid (25507-04-4)

Guidance literature:

3,4-O-p-Anisyliden-clindamycin*HCl, Pyridin, Palmitoylchlorid, HCl;

DOI:10.1002/jps.2600620711