(+/-)-Benzyl N-(benzyloxycarbonyl)valinate

Base Information

• Chemical Name: (+/-)-Benzyl N-(benzyloxycarbonyl)valinate
• CAS No.: 126400-97-3
• Molecular Formula: C₂₀H₂₃NO₄
• Molecular Weight: 341.407
• Mol file: 126400-97-3.mol

Synonyms:(+/-)-Benzyl N-(benzyloxycarbonyl)valinate

Chemical Property of (+/-)-Benzyl N-(benzyloxycarbonyl)valinate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (+/-)-Benzyl N-(benzyloxycarbonyl)valinate

There total 2 articles about (+/-)-Benzyl N-(benzyloxycarbonyl)valinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

D,L-valine (516-06-3,25609-85-2,7004-03-7,921-10-8) + benzyl chloroformate (501-53-1,94274-21-2) → (+/-)-Benzyl N-(benzyloxycarbonyl)valinate (126400-97-3)

Guidance literature:

With dmap; triethylamine; In dimethyl sulfoxide; at 50 ℃; for 1.5h;

DOI:10.1021/jo00097a064

Reference yield:

N-benzyloxycarbonylvaline (1149-26-4,1685-33-2,92077-76-4,3588-63-4) + toluene-4-sulfonic acid (104-15-4) + benzyl alcohol (100-51-6,185532-71-2) → (+/-)-Benzyl N-(benzyloxycarbonyl)valinate (126400-97-3)

Guidance literature:

With benzene;

DOI:10.1021/jo50012a002

Reference yield:

(+/-)-Benzyl N-(benzyloxycarbonyl)valinate (126400-97-3) → valine benzyl ester (17645-51-1)

Guidance literature:

With hydrogen bromide; acetic acid;

DOI:10.1021/jo50012a002

upstream raw materials:

N-benzyloxycarbonylvaline

toluene-4-sulfonic acid

benzyl alcohol

D,L-valine

Downstream raw materials:

valine benzyl ester

Refernces