Tricreamalate

Base Information

• Chemical Name: Tricreamalate
• CAS No.: 21645-51-2
• Deprecated CAS: 106152-09-4,12252-70-9,128083-27-2,1302-29-0,13783-16-9,151393-94-1,51330-22-4,8012-63-3,8064-00-4,159704-77-5,546141-62-2,12040-59-4,16657-47-9,546141-68-8,1071843-34-9,156259-59-5,1847408-13-2,227961-51-5,2243017-67-4,1333-84-2,507478-50-4
• Molecular Formula: Al(OH)3
• Molecular Weight: 78.01
• Hs Code.: 28183000
• NSC Number: 664400
• Wikipedia: Gibbsite
• ChEMBL ID: CHEMBL1200706
• Mol file: 21645-51-2.mol

Synonyms:Aldrox;Algeldrate;Alhydrogel;Alugel;Alumina, Hydrated;Aluminum Hydroxide;Amphojel;Basalgel;Brasivil;Dialume;Hydrated Alumina;Hydroxide, Aluminum;Nephrox;Pepsamer;Rocgel

Chemical Property of Tricreamalate

Chemical Property:

• Appearance/Colour: white amorphous powder
• Vapor Pressure: <0.1 hPa (20 °C)
• Melting Point: 300 °C
• Boiling Point: 2980℃[at 101 325 Pa]
• PSA: 60.69000
• Density: 2.40 g/cm³
• LogP: -0.53040
• Storage Temp.: Store at +5°C to +30°C.
• Solubility.: 0.0015g/l
• Water Solubility.: insoluble
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 81.0132325
• Heavy Atom Count: 4
• Complexity: 3.2

Purity/Quality:

99% ^*data from raw suppliers

C4d ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Mineral Dusts -> Other Mineral Dusts
• Canonical SMILES: O.O.O.[Al]
• Uses: 1. Chemical raw materials Aluminum hydroxide has many advantages including large-scale production, adequate raw materials, high product purity and good solubility in acid. Therefore, aluminum hydroxide can be used as an important raw material for the preparation of aluminum salts, such as barium aluminate, aluminum sulfate and so on. 2. Flame retardants Aluminum hydroxide powder is commonly regarded as an ideal flame retardant filler for plastics, unsaturated polyester, rubber and other organic polymers because of its filling, flame retardant and smoke-eliminating functions and non-toxic property. Flame retardant mechanism of aluminum hydroxide is as follows: when the temperature exceeds 200 ℃, the aluminum hydroxide begin to perform endothermic decomposition and release three crystal water, and its decomposition rate reaches the largest at 250℃. This reaction is a strong endothermic reaction, thereby inhibiting the polymer temperature rise, reducing its decomposition rate and only producing water vapor, not generating toxic and harmful gases. 3. Ceramics Aluminum hydroxide can transform into alumina, which has high thermal chemical stability, thermal strength, creep resistance and dielectric properties and low thermal expansion coefficient. Alumina is an important material for the synthesis of ceramics. In the process of ceramic synthesis, we can control the phase formation of the composite by aluminum hydroxide activation and crystallization process controlling. 4. Sewage treatment Aluminum hydroxide exists in water mainly in form of Al(OH)4-, which can precipitate toxic heavy metals in sewage by coprecipitation method to achieve the effect of water purification after further filter. Aluminum hydroxide has a high specific surface area, and can adsorb colloid, suspended solids, dyes and organic substances in sewage on its surface. 5. Medicine Aluminum hydroxide can neutralize gastric acid and is non-toxic, for which it is always used as the traditional medicine for the treatment of stomach. The aluminum hydroxide as adjuvant can also improve the immunogenicity of the vaccine, the action mechanism of which is as follows: aluminum hydroxide adsorbs antigen on its surface to allow the antigen slow release so that it can play the role of extending efficacy. 6. Catalyst carrier In the preparation of aluminum hydroxide, we can obtain various target products with diffrernt surface area, pore volume, pore structure and crystal structure by controlling the temperature, concentration and pH of the reactants, which can be effectively used as a catalyst carrier for the hydrogenation of unsaturated carbonyl compounds and the preparation of fullerenes and the like. 7. Paper industry Aluminum hydroxide has high whiteness, ultrafine particle size as well as complete crystal form, and has a strong compatibility with brightening agent. Aluminum hydroxide, as an additive coating and resin, can effectively improve the whiteness, opacity, smoothness and ink absorption of coated paper. Mainly used as an Active medicament in an Antacid Formulations, also used in manufacturing of Lake Colors, Inks, glass, effluent treatment, and fire retardants. aluminum hydroxide is an inorganic compound used to make a product less transparent. It is also used by formulators as a humectant, and to soften, smooth, and protect the skin. In addition it helps control product viscosity. often found in facial masks and make-up preparations. As absorbent, in chromatography, manufacturing of glass, paper, inks, ceramics, lubricants, cosmeticsAluminum hydroxide is used as a desiccant powder, filler in paper, plastics, rubber and cosmetics. It is used as a smoke suppressant and mordant dye. It is also used in drugs as antacid and antihyperphosphatemic. It is also used as a Claus catalyst support for waterproof fabrics. It is an important starting material for the preparation of other aluminum compounds, calcined alumina, aluminum sulfate, polyaluminum chloride, zeolites, sodium aluminate, activated alumina and aluminum nitrate. In addition, it is used as a fire retardant.
• Production method: (1) Add alkaline solution to the aluminum sulfate solution under stirring to form precipitation. The precipitation is washed, filtered and dried at low temperature, and then crushed to obtain the finished product. The dewatered paste may also be used as the product directly. The solution concentration, reaction temperature and drying temperature in the preparation process all affect the product quality. (2) Ammonium bicarbonate method: sulfuric acid reacts with aluminum powder or aluminum ash to generate aluminum sulfate, and then aluminum sulfate perform metathesis reaction with ammonium bicarbonate to obtain aluminum hydroxide. 2Al(OH)3+3H2SO4→A12(SO4)3+6H2O A12(SO4)3+6NH4HCO3→2AI(OH)3++3(NH4)2SO4+6CO2↑ Sodium aluminate method: caustic soda and aluminum ash react at the ratio of 2: 1 at 100 ° C to obtain sodium aluminate solution. Sulfuric acid and aluminum ash react at the ratio of 1.25: 1 at 110 ° C to produce aluminum sulfate solution. Then, the sodium aluminate solution and the aluminum sulfate solution are neutralized to pH 6.5 to produce aluminum hydroxide precipitate. The obtained precipitate is washed with water, filtered and dried at 70-80℃ for 12 hours, and then crushed to prepare the aluminum hydroxide product. A12O3+2NaOH→2NaAO2+H2O Al2O3+3H2SO4→A12(SO4)3+3H2O 6NaAIO2+A12(SO4)3+12H2O→8Al(OH)3↓+3Na2SO4 Recovery method: the recycled aluminum chloride is dissolved in water, decolorized with activated carbon and filtered to remove impurities, and then react with sodium carbonate to produce raw aluminum hydroxide. The raw products are filtered, washed and dried to obtain the final aluminum hydroxide products. 2A1C13+3Na2CO3+3H2O→2AI(OH)3↓+6NaCl+3CO2↑
• Clinical Use: Phosphate binding agent Antacid
• Drug interactions: Potentially hazardous interactions with other drugs Cytotoxics: concentration of dasatinib and erlotinib possibly reduced - give at least 4 hours before or 2 hours after erlotinib.