Notoginsenoside R2

Base Information

• Chemical Name: Notoginsenoside R2
• CAS No.: 80418-25-3
• Molecular Formula: C41H70 O13
• Molecular Weight: 770.999
• Mol file: 80418-25-3.mol

Synonyms:20(S)-NotoginsenosideR2; Ginsenoside Ng-R2; Notoginsenoside R2

Chemical Property of Notoginsenoside R2

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 878.731°C at 760 mmHg
• Flash Point: 485.239°C
• PSA: 218.99000
• Density: 1.314g/cm³
• LogP: 1.75890

Purity/Quality:

95%-98% ^*data from raw suppliers

(S)-NotoginsenosideR2 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: S-Notoginsenoside R2 is used as a folk medicine reported to possess immunomodulatory, cardioprotective, hepatoprotective, anti-diabetic and anticancer activities.

Technology Process of Notoginsenoside R2

There total 2 articles about Notoginsenoside R2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

notoginsenoside R1 (80418-24-2) → 20(R)-protopanaxatriol 6-O-β-D-xylopyranosyl(1-2)-β-D-glucopyranoside (80418-25-3) + 20(S)-notoginsenoside R2 (80418-25-3)

Guidance literature:

With acetic acid; In water; at 70 ℃; for 5h; Title compound not separated from byproducts;

DOI:10.1248/cpb.29.2844

Reference yield:

notoginsenoside R1 (80418-24-2) → 20(R)-protopanaxatriol 6-O-β-D-xylopyranosyl(1-2)-β-D-glucopyranoside (80418-25-3) + 20(S)-notoginsenoside R2 (80418-25-3)

Guidance literature:

With acetic acid; In water; at 70 ℃; for 5h; Title compound not separated from byproducts;

DOI:10.1248/cpb.29.2844

Reference yield:

20(S)-notoginsenoside R2 (80418-25-3) → ginsenoside Rh1 (80952-71-2,63223-86-9)

Guidance literature:

With Sphingomonas sp. JB13 GH39 β-xylosidase; water; at 30 ℃; for 24h; pH=4.5; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/acs.jafc.9b00027 DOI:10.1021/acs.jafc.9b00027

upstream raw materials:

notoginsenoside R₁

Downstream raw materials:

ginsenoside Rh₁

Refernces