2-nitro-1,3-diphenoxybenzene

Base Information

• Chemical Name: 2-nitro-1,3-diphenoxybenzene
• CAS No.: 1040027-97-1
• Molecular Formula: C₁₈H₁₃NO₄
• Molecular Weight: 307.306
• Mol file: 1040027-97-1.mol

Synonyms:2-nitro-1,3-diphenoxybenzene

Chemical Property of 2-nitro-1,3-diphenoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-1,3-diphenoxybenzene

There total 1 articles about 2-nitro-1,3-diphenoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,6-difluoro-1-nitrobenzene (19064-24-5) + phenol (108-95-2,27073-41-2) → 2-nitro-1,3-diphenoxybenzene (1040027-97-1)

Guidance literature:

phenol; With sodium hydride; In dimethyl sulfoxide; mineral oil; at 65 ℃; for 1h;

2,6-difluoro-1-nitrobenzene; In dimethyl sulfoxide; mineral oil; at 130 ℃; for 2h;

DOI:10.1021/ol801286k

Reference yield: 100.0%

2-nitro-1,3-diphenoxybenzene (1040027-97-1) → 2,6-diphenoxyaniline (94905-24-5)

Guidance literature:

With palladium on activated charcoal; hydrogen; under 3750.38 Torr;

DOI:10.1021/acscatal.9b00129

Reference yield:

2-nitro-1,3-diphenoxybenzene (1040027-97-1) → C39H27NO3

Guidance literature:

Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / 3750.38 Torr

2: methanol / Acidic conditions

With palladium on activated charcoal; hydrogen; In methanol;

DOI:10.1021/acscatal.9b00129

upstream raw materials:

2,6-difluoro-1-nitrobenzene

phenol

Downstream raw materials:

2,6-diphenoxyaniline

Refernces

• 1、 Carroll, William R.,Pellechia, Perry,Shimizu, Ken D.. "A rigid molecular balance for measuring face-to-face arene-arene interactions". supporting information; experimental part. p. 3547 - 3550. Retrieved 2009/05/07.