benzyl (E)-5-bromo-2-pentenoate

Base Information

• Chemical Name: benzyl (E)-5-bromo-2-pentenoate
• CAS No.: 132640-88-1
• Molecular Formula: C₁₂H₁₃BrO₂
• Molecular Weight: 269.138
• Mol file: 132640-88-1.mol

Synonyms:benzyl (E)-5-bromo-2-pentenoate

Chemical Property of benzyl (E)-5-bromo-2-pentenoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl (E)-5-bromo-2-pentenoate

There total 3 articles about benzyl (E)-5-bromo-2-pentenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-bromopropanal (65032-54-4) + (carbobenzyloxymethylene)triphenylphosphorane (15097-38-8) → benzyl (E)-5-bromo-2-pentenoate (132640-88-1)

Guidance literature:

In toluene; at 21 ℃; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.04.069

Reference yield:

3-bromopropanal (65032-54-4) + (carbobenzyloxymethylene)triphenylphosphorane (15097-38-8) → benzyl (Z)-5-bromo-2-pentenoate (132640-88-1) + benzyl (E)-5-bromo-2-pentenoate (132640-88-1)

Guidance literature:

In benzene; for 8h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

Reference yield:

3-bromopropanal (65032-54-4) + (carbobenzyloxymethylene)triphenylphosphorane (15097-38-8) → benzyl (Z)-5-bromo-2-pentenoate (132640-88-1) + benzyl (E)-5-bromo-2-pentenoate (132640-88-1)

Guidance literature:

In benzene; for 8h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

upstream raw materials:

3-bromopropanal

(carbobenzyloxymethylene)triphenylphosphorane

Downstream raw materials:

C₂₈H₃₄N₂O₄

C₂₀H₂₅NO₅

C₂₀H₂₅NO₅

benzyl 2-cyclopropylacetate

Refernces

• 1、 Bunce, Richard A.,Irwin, Derek A.. "A One-pot Synthesis of (E)-5-Bromo-2-pentenoate Esters". . p. 2979 - 2982. Retrieved 2007/10/02.