7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one

Base Information Edit

Chemical Name:7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one
CAS No.:120004-79-7
Molecular Formula:C13H16ClNO2
Molecular Weight:253.729
Hs Code.:2933790090
European Community (EC) Number:601-645-6
DSSTox Substance ID:DTXSID70440419
Nikkaji Number:J961.890B
Wikidata:Q72464730
Mol file:120004-79-7.mol

Synonyms:120004-79-7;7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one;3,4-dihydro-7-(4-chlorobutoxy)-2(1h)-quinolinone;7-(4-chlorobutoxy)-3,4-dihydro-1H-quinolin-2-one;7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone;2(1H)-Quinolinone, 7-(4-chlorobutoxy)-3,4-dihydro-;7-(4-chlorobutoxy)-1,2,3,4-tetrahydroquinolin-2-one;7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone;7-(4-Chlorobutoxy)-3,4-dihydrocarbostyril;SCHEMBL238817;7-(4-Chlorobutoxy)-3,4-dihydro C2(1H)-quinolinone;DTXSID70440419;SRMLSNBGMDJSJH-UHFFFAOYSA-N;MFCD07787529;AKOS015901402;AC-8059;AS-68439;7-(4-chlorobutoxy)-3,4-dihydrocarbostyril;7-(4-chloro butoxy)-3,4-dihydrocarbostyril;AM20090767;CS-0036678;FT-0655809;W14961;EN300-1659328;A804407;7-(4-chlorobutoxy)-3,4-dihydro-(1H)-quinolinone;7-(4-Chlorobutoxy)-3,4-dihydroquinoline-2(1H)-one;7-(4-chloranylbutoxy)-3,4-dihydro-1H-quinolin-2-one;3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone

Suppliers and Price of 7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone
1g
$ 175.00

Medical Isotopes, Inc.
7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone
50 mg
$ 190.00

Crysdot
7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one 97%
1g
$ 340.00

Chemenu
3,4-dihydro-7-(4-chlorobutoxy)-2(1h)-quinolinone 97%
10g
$ 1571.00

Chemenu
3,4-dihydro-7-(4-chlorobutoxy)-2(1h)-quinolinone 97%
5g
$ 943.00

Biosynth Carbosynth
3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone
5 mg
$ 115.00

Biosynth Carbosynth
3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone
2 mg
$ 60.00

Biosynth Carbosynth
3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone
10 mg
$ 180.00

Biosynth Carbosynth
3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone
50 mg
$ 540.00

Biosynth Carbosynth
3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone
25 mg
$ 350.00

Total 95 raw suppliers

Chemical Property of 7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one Edit

Chemical Property:

Appearance/Colour:White to off-white crystalline powder
Vapor Pressure:0mmHg at 25°C
Melting Point:100-102 °C(Solv: ethanol (64-17-5))
Refractive Index:1.543
Boiling Point:448.925 °C at 760 mmHg
PKA:14.41±0.20(Predicted)
Flash Point:225.302 °C
PSA：38.33000
Density:1.187 g/cm³
LogP:3.10710
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:253.0869564
Heavy Atom Count:17
Complexity:260

Purity/Quality:

99% ^*data from raw suppliers

7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC2=C1C=CC(=C2)OCCCCCl
Uses 3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone is used in the synthesis of aripiprazole, an antipsychotic oral drug used in the treatment of Schizophrenia. 7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone is used in the synthesis of aripiprazole, an antipsychotic oral drug used in the treatment of Schizophrenia.

Technology Process of 7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one

There total 5 articles about 7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6940-78-9
4-chlorobutyl bromide

: 22246-18-0
7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

: 120004-79-7
7-(4-chlorobutoxy)-3,4-dihydroquinoline-2(1H)-one

Guidance literature:: With lithium hydroxide; In water; N,N-dimethyl-formamide; at 40 - 50 ℃; for 3h; Reagent/catalyst; Solvent; Sealed tube; Large scale;