Z-D-PipCHN₂

Base Information

• Chemical Name: Z-D-PipCHN₂
• CAS No.: 111492-04-7
• Molecular Formula: C₁₅H₁₇N₃O₃
• Molecular Weight: 287.318
• Mol file: 111492-04-7.mol

Synonyms:Z-D-PipCHN₂

Chemical Property of Z-D-PipCHN₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Z-D-PipCHN₂

There total 1 articles about Z-D-PipCHN₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (R)-1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid (28697-07-6,28697-09-8,28697-11-2,71170-88-2) → Z-D-PipCHN2 (111492-04-7)

Guidance literature:

(R)-1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -30 ℃; for 1h;

diazomethane; In tetrahydrofuran; diethyl ether; at 20 ℃;

With acetic acid; In tetrahydrofuran; diethyl ether;

Reference yield: 60.0%

Z-D-PipCHN2 (111492-04-7) → Z-D-PipCH2Cl (111491-95-3)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran;

Reference yield:

methanol (67-56-1) + Z-D-PipCHN2 (111492-04-7) → 2-methoxycarbonylmethyl-piperidine-1-carboxylic acid benzyl ester (934422-94-3)

Guidance literature:

With silver benzoate; at 20 ℃; for 3h;

upstream raw materials:

diazomethane

(R)-1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid

Downstream raw materials:

Z-D-PipCH₂Cl

Z-D-PipCH₃

2-methoxycarbonylmethyl-piperidine-1-carboxylic acid benzyl ester

Refernces