6-Nitro-2,5-pyridinediamine

Base Information

• Chemical Name: 6-Nitro-2,5-pyridinediamine
• CAS No.: 69825-83-8
• Molecular Formula: C₅H₆N₄O₂
• Molecular Weight: 154.128
• Hs Code.: 2933399090
• UNII: 114992974A
• DSSTox Substance ID: DTXSID30220113
• Wikidata: Q27251249
• Mol file: 69825-83-8.mol

Synonyms:6-nitropyridine-2,5-diamine;69825-83-8;6-NITRO-2,5-PYRIDINEDIAMINE;6-Nitro-2,5-diaminopyridine;2,5-diamino-6-nitropyridine;2,5-Pyridinediamine, 6-nitro-;6-Nitro-2,5-pyridinediamine [INCI];UNII-114992974A;114992974A;SCHEMBL109187;DTXSID30220113;DRSOPPBVZYEMNZ-UHFFFAOYSA-N;2, 5- diamino- 6- nitro- pyridine;AKOS006289711;SB54507;FT-0659543;A836665;Q27251249

Chemical Property of 6-Nitro-2,5-pyridinediamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 210-212 °C
• Boiling Point: 485.003oC at 760 mmHg
• PKA: 2.73±0.10(Predicted)
• Flash Point: 247.121°C
• PSA: 110.75000
• Density: 1.556g/cm3
• LogP: 1.83980
• Storage Temp.: 2-8°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 154.04907545
• Heavy Atom Count: 11
• Complexity: 157

Purity/Quality:

99% ^*data from raw suppliers

6-NITRO-2,5-PYRIDINEDIAMINE 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=NC(=C1N)[N+](=O)[O-])N

Technology Process of 6-Nitro-2,5-pyridinediamine

There total 5 articles about 6-Nitro-2,5-pyridinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

pyrido<2,3-c>furoxane (27808-53-3) → 2,5-diamino-6-nitropyridine (69825-83-8)

Guidance literature:

With ammonia; In water; at 18 - 25 ℃;

DOI:10.1007/BF00505694

Reference yield:

5-[5-amino-6-nitro-2-(pyridinyl)amino]-5-oxopentanoic acid (607383-62-0) → 2,5-diamino-6-nitropyridine (69825-83-8)

Guidance literature:

With sodium hydroxide; immobilized glutaryl amidase; In water; at 37 ℃; for 24h; pH=7.5; Product distribution / selectivity; Enzymatic reaction; potassium phosphate buffer;

Reference yield:

5-[(6-amino-5-(3-pyridinyl-diazenyl)-2-pyridinyl)amino]-5-oxopentanoic acid (607383-65-3) → 2,5-diamino-6-nitropyridine (69825-83-8)

Guidance literature:

With sodium hydroxide; immobilized glutaryl acylase; In water; at 37 ℃; for 0.5h; pH=7.5; Product distribution / selectivity; Enzymatic reaction; potassium phosphate buffer;

upstream raw materials:

pyrido<2,3-c>furoxane

2-nitro-3-azidopyridine

5-[(6-amino-5-(3-pyridinyl-diazenyl)-2-pyridinyl)amino]-5-oxopentanoic acid

5-[5-amino-6-nitro-2-(pyridinyl)amino]-5-oxopentanoic acid

Refernces

• 1、 -. "Composition and method for dyeing dye-susceptible material". Page/Page column 23. . Retrieved 2008/06/13.
• 2、 Kotovskaya,Mokrushina,Postovskii,Polyakova. "Pyrido[2,3-c]furoxan as a probable intermediate in the reaction of 2-nitro-3-azidopyridine with amines". . p. 480 - 483. Retrieved 2007/10/02.