1-Benzothiophen-6-yl ethyl ether

Base Information

• Chemical Name: 1-Benzothiophen-6-yl ethyl ether
• CAS No.: 26018-78-0
• Molecular Formula: C₁₀H₁₀OS
• Molecular Weight: 178.255
• NSC Number: 108919
• DSSTox Substance ID: DTXSID50296350
• Wikidata: Q82036915
• Mol file: 26018-78-0.mol

Synonyms:26018-78-0;NSC 108919;1-benzothiophen-6-yl ethyl ether;Benzo[b]thiophene,6-ethoxy-;NSC108919;6-ethoxybenzothio-phene;SCHEMBL827195;DTXSID50296350;NSC-108919

Chemical Property of 1-Benzothiophen-6-yl ethyl ether

Chemical Property:

• Vapor Pressure: 0.00532mmHg at 25°C
• Boiling Point: 283.7°C at 760 mmHg
• Flash Point: 125.4°C
• Density: 1.16g/cm³
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 178.04523611
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC2=C(C=C1)C=CS2

Technology Process of 1-Benzothiophen-6-yl ethyl ether

There total 4 articles about 1-Benzothiophen-6-yl ethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H20O3S → 6-Aethoxybenzothiophen (26018-78-0)

Guidance literature:

With polyposphoric acid; In toluene;

Reference yield:

3-Bromophenol (591-20-8) → 6-Aethoxybenzothiophen (26018-78-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / acetone

2: magnesium; sulfur / tetrahydrofuran

3: polyposphoric acid / toluene

With potassium carbonate; sulfur; magnesium; In tetrahydrofuran; acetone; toluene;

Reference yield:

m-ethoxyphenyl bromide (2655-84-7) → 6-Aethoxybenzothiophen (26018-78-0)

Guidance literature:

Multi-step reaction with 2 steps

1: magnesium; sulfur / tetrahydrofuran

2: polyposphoric acid / toluene

With sulfur; magnesium; In tetrahydrofuran; toluene;

upstream raw materials:

3-Bromophenol

m-ethoxyphenyl bromide

Refernces