1,2-Bis(phosphino)ethane

Base Information

• Chemical Name: 1,2-Bis(phosphino)ethane
• CAS No.: 5518-62-7
• Molecular Formula: C2H8 P2
• Molecular Weight: 94.03
• European Community (EC) Number: 682-101-5
• DSSTox Substance ID: DTXSID30402371
• Nikkaji Number: J924.115I
• Wikidata: Q82205771
• Mol file: 5518-62-7.mol

Synonyms:1,2-BIS(PHOSPHINO)ETHANE;5518-62-7;2-phosphanylethylphosphane;ethylenediphosphine;Ethylenebisphosphine;1,2-diphosphinoethane;1,2-bis-phosphanyl-ethane;DTXSID30402371;MFCD00049195;FT-0606313

Chemical Property of 1,2-Bis(phosphino)ethane

Chemical Property:

• Vapor Pressure: 7.21mmHg at 25°C
• Melting Point: -62.4°C
• Boiling Point: 109-110°C
• Flash Point: 109-110°C
• PSA: 27.18000
• LogP: 0.73660
• Sensitive.: Air Sensitive
• Water Solubility.: It is soluble in organic solvents. It is insoluble in water.
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 94.01012425
• Heavy Atom Count: 4
• Complexity: 6

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(phosphino)ethane, 99% ^*data from reagent suppliers

Safty Information:

• Statements: 17-36/37/38
• Safety Statements: 17-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CP)P
• Uses: It is used in chemical research organic Intermediates.

Technology Process of 1,2-Bis(phosphino)ethane

There total 3 articles about 1,2-Bis(phosphino)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1,2-bis(dichlorophosphino)ethane (28240-69-9) → 1,2-diphosphinoethane (5518-62-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at -78 - 20 ℃;

DOI:10.1021/acs.organomet.7b00475

Reference yield:

tetraethyl ethylenebis(phosphonate) (995-32-4) → 1,2-diphosphinoethane (5518-62-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃; for 0.5h;

DOI:10.1021/jm701146c

Reference yield:

→ 1,2-diphosphinoethane (5518-62-7)

Guidance literature:

DOI:10.1002/hlca.19660490203

upstream raw materials:

tetraethyl ethylenebis(phosphonate)

1,2-bis(dichlorophosphino)ethane

Downstream raw materials:

Tetrofosmin

1,2-bis(dichlorophosphino)ethane

1,2-bis((1S,2R)-2-benzylphospholano)ethane

1,2-bis[(2R,5R)-2,5-benzyloxymethylphospholanyl]ethane

Refernces

• 1、 Rinehart, N. Ian,Kendall, Alexander J.,Tyler, David R.. "A Universally Applicable Methodology for the Gram-Scale Synthesis of Primary, Secondary, and Tertiary Phosphines". supporting information. p. 182 - 190. Retrieved 2018/02/06.
• 2、 -. "Organophosphines". . . Retrieved 2008/06/13.