Octadecyl gallate

Base Information

• Chemical Name: Octadecyl gallate
• CAS No.: 10361-12-3
• Molecular Formula: C25H42O5
• Molecular Weight: 422.605
• Hs Code.: 2918290000
• Mol file: 10361-12-3.mol

Synonyms:Octadecylgallate;Gallicacid, octadecyl ester (6CI,7CI,8CI);1-Octadecanol, gallate (6CI);Stearyl gallate;Gallic acidstearyl ester;Nipagallin ST;Octadecyl 3,4,5-trihydroxybenzoate;

Chemical Property of Octadecyl gallate

Chemical Property:

• Vapor Pressure: 3.44E-14mmHg at 25°C
• Melting Point: 95 °C
• Refractive Index: 1.519
• Boiling Point: 583 °C at 760 mmHg
• PKA: 7.93±0.25(Predicted)
• Flash Point: 187.8 °C
• PSA: 86.99000
• Density: 1.048 g/cm³
• LogP: 7.22170
• Storage Temp.: 2-8°C
• Water Solubility.: Insoluble in water

Purity/Quality:

99% ^*data from raw suppliers

Octadecyl3,4,5-Trihydroxybenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Octadecyl gallate

There total 5 articles about Octadecyl gallate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.2%

1-octadecanol (112-92-5) + 3,4,5-trihydroxybenzoic acid (149-91-7) → octadecyl 3,4,5-trihydroxybenzoate (10361-12-3)

Guidance literature:

With cation exchange resin 731; In ethyl acetate; at 80 - 85 ℃; Dean-Stark;

Reference yield: 97.0%

octadecyl 3,4,5-tribenzyloxybenzoate (1063201-10-4) → octadecyl 3,4,5-trihydroxybenzoate (10361-12-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; atmospheric pressure;

DOI:10.1016/j.bmc.2008.07.063

Reference yield:

→ octadecyl 3,4,5-trihydroxybenzoate (10361-12-3)

Guidance literature:

With palladium on activated charcoal; ethanol; Hydrogenation;

DOI:10.1021/ja01207a043

upstream raw materials:

1-octadecanol

3,4,5-trihydroxybenzoic acid

octadecyl 3,4,5-tribenzyloxybenzoate

Downstream raw materials:

octadecyl 3-O-(β-D-glucopyranosyl)-4,5-dihydroxybenzoate

octadecyl 3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside)-4,5-dihydroxybenzoate

Refernces

• 1、 Zhao, Xiao-Long,Li, Chun-Qing,Song, Xiao-Mei,Yan, Shuang-Mei,Luo, Du-Qiang. "Design, Synthesis, and Antifungal Activity of Alkyl Gallates Against Plant Pathogenic Fungi In Vitro and In Vivo". . p. 38 - 43. Retrieved 2021/02/01.
• 2、 Dodo, Kosuke,Minato, Taro,Noguchi-Yachide, Tomomi,Suganuma, Masami,Hashimoto, Yuichi. "Antiproliferative and apoptosis-inducing activities of alkyl gallate and gallamide derivatives related to (-)-epigallocatechin gallate". . p. 7975 - 7982. Retrieved 2008/12/23.