4,4'-Thiodibenzenethiol

Base Information

• Chemical Name: 4,4'-Thiodibenzenethiol
• CAS No.: 19362-77-7
• Molecular Formula: C12H10S3
• Molecular Weight: 250.409
• Hs Code.: 2930909090
• Mol file: 19362-77-7.mol

Synonyms:Benzenethiol,4,4'-thiodi- (6CI,8CI);4,4'-Dimercaptodiphenyl sulfide;4,4'-Thiobis(phenylthiol);4,4'-Thiobisbenzenethiol;Bis(4-mercaptophenyl) sulfide;p,p'-Dimercaptodiphenyl sulfide;

Chemical Property of 4,4'-Thiodibenzenethiol

Chemical Property:

• Melting Point: 112-114 °C(lit.)
• Boiling Point: 431.2 °C at 760 mmHg
• PKA: 5.86±0.10(Predicted)
• Flash Point: 214.6 °C
• PSA: 102.90000
• Density: 1.3 g/cm³
• LogP: 4.41520
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

4,4''-Thiobisbenzenethiol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: intermedia 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein. 4,4''-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.

Technology Process of 4,4'-Thiodibenzenethiol

There total 7 articles about 4,4'-Thiodibenzenethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4,4'-bis(acetylthio)diphenyl sulfide → 4,4'-dimercaptodiphenyl sulfide (19362-77-7)

Guidance literature:

With sodium hydroxide; In water; for 3h; Reagent/catalyst; Reflux; Large scale;

Reference yield: 93.0%

4,4'-bis(chlorosulfonyl)diphenyl sulfide (3119-65-1) → 4,4'-dimercaptodiphenyl sulfide (19362-77-7)

Guidance literature:

With hydrogenchloride; water; zinc; In toluene; at 85 ℃; for 2h;

Reference yield: 80.0%

C14H18N4S3 → 4,4'-dimercaptodiphenyl sulfide (19362-77-7)

Guidance literature:

With water; sodium hydroxide; In ethanol; at 80 - 90 ℃; for 2h;

upstream raw materials:

4,4'-bis(chlorosulfonyl)diphenyl sulfide

4,4'-sulfanediyl-bis-benzenesulfinic acid

hydrogenchloride

diphenyl sulfide

Downstream raw materials:

bis(4-vinylthiophenyl)sulfide

bis-(4-β,β-dichlorovinylsulfonylphenyl) sulfone

4,4'-bis(3-methyl-4-nitrophenylsulfanyl)diphenylsulfide

4,4'-bis[(acryloyloxyethylthio)diphenyl]sulfide

Refernces

• 1、 -. "Method for synthesizing 4,4'-thiodibenzenethiol". . . Retrieved 2017/08/29.
• 2、 Alov,Nikiforov,Novikov,Kobylinskii,Moskvichev,Kryukova,Yasinskii,Budanov. "Synthesis, acidic and basic properties of thiols and sulfinic acids from the series of diphenyl bridging compounds". . p. 1160 - 1164. Retrieved 2007/10/03.