ETHYL PENTAFLUOROPROPIONYLACETATE

Base Information

• Chemical Name: ETHYL PENTAFLUOROPROPIONYLACETATE
• CAS No.: 663-35-4
• Molecular Formula: C7H7F5O3
• Molecular Weight: 234.123
• Hs Code.: 29183000
• Mol file: 663-35-4.mol

Synonyms:Ethyl4,4,5,5,5-pentafluoro-3-oxovalerate;Ethyl pentafluoropropionylacetate;Ethyl4,4,5,5,5-pentafluoro-3-oxopentanoate;Valericacid, 4,4,5,5,5-pentafluoro-3-oxo-, ethyl ester (6CI,8CI);4,4,5,5,5-Pentafluoro-3-oxopentanoic acid ethyl ester;4,4,5,5,5-Pentafluoro-3-oxovaleric acid ethyl ester;Ethyl3-oxo-4,4,5,5,5-pentafluoropentanoate;

Chemical Property of ETHYL PENTAFLUOROPROPIONYLACETATE

Chemical Property:

• Vapor Pressure: 3.09mmHg at 25°C
• Refractive Index: n20/D 1.367(lit.)
• Boiling Point: 155 °C at 760 mmHg
• PKA: 7.66±0.46(Predicted)
• Flash Point: 46.9 °C
• PSA: 43.37000
• Density: 1.361 g/cm³
• LogP: 1.70630

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl pentafluoropropionyl acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL PENTAFLUOROPROPIONYLACETATE

There total 4 articles about ETHYL PENTAFLUOROPROPIONYLACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

ethyl Pentafluoropropionate (426-65-3) + ethyl acetate (141-78-6) → ethylpentafluoropropionylacetate (663-35-4)

Guidance literature:

With sodium ethanolate; In tert-butyl methyl ether; at 20 - 50 ℃;

Reference yield:

ethyl Pentafluoropropionate (426-65-3) → ethylpentafluoropropionylacetate (663-35-4)

Guidance literature:

With sulfuric acid; In diethyl ether; ethyl acetate;

Reference yield:

perfluoropropionic acid methyl ester (378-75-6) + ethyl acetate (141-78-6) → ethylpentafluoropropionylacetate (663-35-4)

Guidance literature:

ethyl acetate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

perfluoropropionic acid methyl ester; In tetrahydrofuran; at -78 ℃; for 3h;

DOI:10.1016/j.tet.2006.12.045

upstream raw materials:

ethyl Pentafluoropropionate

ethyl acetate

perfluoropropionic acid methyl ester

Downstream raw materials:

1-phenyl-3-pentafluoroethyl-4-hydro-5-hydroxypyrazole

N-phenyl-3-difluoromethyl-5-pentafluoroethyl-4-pyrazolecarboxylic acid ethyl ester

Refernces

• 1、 Jagodzinska, Monika,Huguenot, Florent,Zanda, Matteo. "Studies on a three-step preparation of β-fluoroalkyl acrylates from fluoroacetic esters". . p. 2042 - 2046. Retrieved 2007/10/03.
• 2、 -. "3-perfluoroalkyl-5-hydroxyisoxazoles". . . Retrieved 2008/06/13.