N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt

Base Information

• Chemical Name: N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
• CAS No.: 66992-27-6
• Molecular Formula: C6H14NNaO5S
• Molecular Weight: 235.237
• Hs Code.: 29225090
• Mol file: 66992-27-6.mol

Synonyms:Ethanesulfonicacid, 2-[bis(2-hydroxyethyl)amino]-, monosodium salt (9CI);

Chemical Property of N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt

Chemical Property:

• PKA: 7.1 (Free acid)(at 25℃)
• PSA: 109.28000
• LogP: -1.10100
• Storage Temp.: Store at RT.
• Solubility.: H2O: 0.35 g/mL, clear, colorless

Purity/Quality:

99%, ^*data from raw suppliers

BES sodium salt ≥99% (titration) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xn
• Hazard Codes: F,Xn
• Statements: 10-15
• Safety Statements: 22-24/25-43-7/8

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt

There total 2 articles about N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

oxirane (75-21-8,99932-75-9) + sodium taurinate (7347-25-3) → sodium N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonate (66992-27-6)

Guidance literature:

sodium taurinate; With water; at 0 ℃; for 2h;

oxirane;

Reference yield: 81.0%

sodium vinylsulfonate (3039-83-6) + 2,2'-iminobis[ethanol] (111-42-2) → sodium N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonate (66992-27-6)

Guidance literature:

for 24h; Reflux;

DOI:10.1134/S107032841811009X

Reference yield: 80.0%

sodium N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonate (66992-27-6) → 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid (10191-18-1)

Guidance literature:

With water;

upstream raw materials:

oxirane

sodium taurinate

sodium vinylsulfonate

2,2'-iminobis[ethanol]

Downstream raw materials:

2-(di(2-hydroxyethyl)amino)ethanesulfonic acid

Refernces

• 1、 -. "A biological buffer preparation method". Paragraph 0017-0026. . Retrieved 2017/08/02.