2-Morpholinocyclopentanol

Base Information

• Chemical Name: 2-Morpholinocyclopentanol
• CAS No.: 161193-34-6
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.24
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID40550438
• Mol file: 161193-34-6.mol

Synonyms:2-Morpholinocyclopentanol;161193-34-6;1-(morpholin-4-yl)-2-hydroxycyclopentane;2-morpholin-4-ylcyclopentan-1-ol;2-(MORPHOLIN-4-YL)CYCLOPENTAN-1-OL;Cyclopentanol, 2-(4-morpholinyl)-;SCHEMBL12014346;DTXSID40550438;2-(4-morpholinyl)-1-cyclopentanol;AKOS009117776;A810238;F8882-6246

Chemical Property of 2-Morpholinocyclopentanol

Chemical Property:

• Vapor Pressure: 0.000715mmHg at 25°C
• Refractive Index: 1.538
• Boiling Point: 273.817 °C at 760 mmHg
• Flash Point: 119.4 °C
• PSA: 32.70000
• Density: 1.158 g/cm³
• LogP: 0.16990
• Storage Temp.: 2-8°C
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 171.125928785
• Heavy Atom Count: 12
• Complexity: 146

Purity/Quality:

99% ^*data from raw suppliers

2-Morpholinocyclopentanol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C(C1)O)N2CCOCC2

Technology Process of 2-Morpholinocyclopentanol

There total 1 articles about 2-Morpholinocyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Cyclopentene oxide (285-67-6) + morpholine (110-91-8,99108-56-2) → 2-(morpholin-4-yl)cyclopentanol (161193-34-6)

Guidance literature:

With acetic acid; In water; at 20 ℃; for 0.5h; Solvent; Reagent/catalyst;

Reference yield:

2-(morpholin-4-yl)cyclopentanol (161193-34-6) → α-morpholinocyclopentanone (55737-23-0)

Guidance literature:

With oxalyl dichloride; triethylamine; In dichloromethane; dimethyl sulfoxide; at 20 ℃; for 2.5h;

DOI:10.1002/anie.200702491

upstream raw materials:

Cyclopentene oxide

morpholine

Downstream raw materials:

α-morpholinocyclopentanone

Refernces

• 1、 Liu, Sheng,Xie, Jian-Hua,Wang, Li-Xin,Zhou, Qi-Lin. "Dynamic kinetic resolution allows a highly enantioselective synthesis of cis-α-aminocycloalkanols by ruthenium-catalyzed asymmetric hydrogenation". . p. 7506 - 7508. Retrieved 2008/09/17.