N-BENZYL-1-PHENYLETHYLAMINE

Base Information

• Chemical Name: N-BENZYL-1-PHENYLETHYLAMINE
• CAS No.: 3193-62-2
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.307
• Hs Code.: 2921499090
• Mol file: 3193-62-2.mol

Synonyms:Dibenzylamine,a-methyl- (6CI,7CI,8CI); (?à)-N-Benzyl-1-phenylethylamine; (?à)-N-Benzyl-a-methylbenzylamine; Benzyl(1-phenylethyl)amine;N-(a-Methylbenzyl)(benzyl)amine;N-Benzyl-N-(1-phenylethyl)amine; N-Benzyl-N-(a-methylbenzyl)amine; N-Benzyl-a-methylbenzylamine; a-Methyldibenzylamine

Chemical Property of N-BENZYL-1-PHENYLETHYLAMINE

Chemical Property:

• PSA: 12.03000
• LogP: 3.92830

Purity/Quality:

98%Min ^*data from raw suppliers

N-Benzyl-1-phenylethanamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-BENZYL-1-PHENYLETHYLAMINE

There total 88 articles about N-BENZYL-1-PHENYLETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-1-phenyl-N-(1-phenylethylidene)methanamine (14428-98-9,98325-59-8,98359-08-1) → N-benzyl-1-phenylethylamine (3193-62-2,17480-69-2,19302-20-6,38235-77-7)

Guidance literature:

With potassium tert-butylate; hydrogen; [RuCl₂(Ph₂PCH₂CH₂NH₂)₂]; at 20 ℃; for 12h; under 2280 Torr;

DOI:10.1002/adsc.200404274

Reference yield: 98.0%

rac-methylbenzylamine (618-36-0) + benzyl alcohol (100-51-6,185532-71-2) → N-benzyl-1-phenylethylamine (3193-62-2,17480-69-2,19302-20-6,38235-77-7)

Guidance literature:

With μ-diiodo-di((η5-pentamethylcyclopentadienyl)(iodo)iridium); In water; at 115 ℃; for 10h; Inert atmosphere;

DOI:10.1039/b923083a

Reference yield: 98.0%

benzonitrile (100-47-0) + rac-methylbenzylamine (618-36-0) → N-benzyl-1-phenylethylamine (3193-62-2,17480-69-2,19302-20-6,38235-77-7)

Guidance literature:

With 3 % platinum on carbon; hydrogen; In toluene; at 105 ℃; under 4500.45 Torr; Flow reactor;

DOI:10.1039/c2cy20431b

upstream raw materials:

(R)-1-phenyl-ethyl-amine

benzyl chloride

rac-methylbenzylamine

acetophenone

Downstream raw materials:

(S)-N-benzyl-1-phenylethylamine

(R)-N-benzyl-1-phenylethylamine

acetophenone

rac-methylbenzylamine

Refernces

• 1、 Wu, Xiao-Feng,Yuan, Yang,Zhao, Fengqian. "Copper-catalyzed enantioselective carbonylation toward α-chiral secondary amides". . p. 12676 - 12681. Retrieved 2021/10/19.
• 2、 Bestvater, Brian P.,Clarke, Joshua J.,Crudden, Cathleen M.,DeJesus, Joseph F.,Devaraj, Karthik,Eisenberger, Patrick,Kojima, Ryoto. "Hydrosilylation and Mukaiyama aldol-type reaction of quinolines and hydrosilylation of imines catalyzed by a mesoionic carbene-stabilized borenium ion". . p. 6786 - 6791. Retrieved 2021/08/20.